Drugs / Palomid 529
last change Sep 2012 re-read 3 minutes ago

Palomid 529

also known as P-529 · SG 00529

Small molecule targets MTOR via inhibition

Developed for
age-related macular degeneration
Investigated by
National Eye Institute (NEI) · Paloma Pharmaceuticals, Inc.

Trials 2

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01271270 Dec 2010 → Sep 2012 age-related macular degeneration National Eye Institute (NEI) Completed No outcome recorded
Phase 1 NCT01033721 Jun 2010 → Dec 2011 age-related macular degeneration Paloma Pharmaceuticals, Inc. Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Palomid 529 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01271270 ↗
1

NCT01033721 ↗

Known as P-529 ChEMBL registry synonym — accepted as the source's own label CHEMBL2141712 ↗
Known as SG 00529 ChEMBL registry synonym — accepted as the source's own label CHEMBL2141712 ↗
Action Inhibit “dual TORC1/2 inhibitor” NCT01033721 ↗
Modality Small molecule “Paloma Pharmaceuticals, Inc. has developed a non-steroidal, wholly synthetic, small molecule drug for application to diseases of aberrant neovasculature, known as Palomid 529.” NCT01271270 ↗
Route Intravitreal “Single Intravitreal and Subconjunctival Doses of Palomid 529” NCT01033721 ↗
Target MTOR “The experimental chemical Palomid 529 inhibits the production of mTOR.” NCT01271270 ↗