Drugs / L-NAME
L-NAME
Trials 1
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT00753948 | Dec 2006 → Aug 2010 | asthma, quadriplegia | VA Office of Research and Development | Completed | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| Phase 2/3 | NCT00237770 Comparator | Jun 2003 → Jun 2010 | hypotensive disorder, spinal cord injury | US Department of Veterans Affairs | Completed | No outcome recorded |
Evidence & citations 7 cited values
Every value below carries the sentence it was read from. 4 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | L-NAME | “N-Nitro L-arginine-methylester (L-NAME)” NCT00753948 ↗1“N-Nitro L-arginine-methylester (L-NAME)” NCT00237770 ↗ |
| Known as | N-Nitro L-arginine-methylester | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00753948 ↗ |
| Known as | Ng-nitro-l-arginine methyl ester | ChEMBL registry synonym — accepted as the source's own label CHEMBL7890 ↗ |
| Known as | nitro-L-arginine methyl ester | “The study objective was to determine the effect of a NOS inhibitor (nitro-L-arginine methyl ester [L-NAME]) on supine mean arterial pressure in persons with chronic tetraplegia...” PMID 17385265 ↗ 2007 |
| Action | Inhibit | “A non-specific inhibitor of the nitric oxide synthase enzyme.” NCT00237770 ↗ |
| Modality | Small molecule | — CHEMBL7890 ↗ |
| Route | Intravenous | “both were infused intravenously over 60 minutes” PMID 17385265 ↗ 2007 |