Drugs / AS1411
last change Nov 2013 re-read 3 minutes ago

AS1411

Aptamer

Developed for
acute myeloid leukemia · cancer · renal cell carcinoma
Investigated by
Antisoma Research

Trials 4

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00881244 Sep 2003 → Jun 2006 cancer Antisoma Research Completed No outcome recorded
Phase 23 trials
Phase 2 NCT01034410 Jan 2010 → Jan 2011 acute myeloid leukemia Antisoma Research Terminated No outcome recorded
Phase 2 NCT00740441 Aug 2008 → Sep 2009 renal cell carcinoma Antisoma Research Unknown No outcome recorded
Phase 2 NCT00512083 Jul 2007 → Apr 2009 acute myeloid leukemia Antisoma Research Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as AS1411 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01034410 ↗
3

NCT00512083 ↗

NCT00881244 ↗

NCT00740441 ↗

Modality Aptamer “AS1411, a DNA aptamer targeting nucleolin (a protein which is overexpressed in many tumor types), was evaluated” PMID 24242861 ↗ Nov 2013
Route Intravenous “AS1411 IV administration” NCT00512083 ↗