Drugs / AMELUBANT
last change Nov 2002 re-read 2 minutes ago

AMELUBANT

also known as BIIL 284 BS · BIIL 284 · LS-49968

Small molecule targets LTB4R via inhibition

Developed for
chronic obstructive pulmonary disease · cystic fibrosis · rheumatoid arthritis · asthma
Investigated by
Boehringer Ingelheim

Trials 17 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 113 trials
Phase 1 NCT02269189 Apr → Nov 2002 cystic fibrosis Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02265679 Oct 2001 → Jul 2002 cystic fibrosis Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02265666 Oct → Nov 2001 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02265640 Oct → Dec 2000 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02273440 May → Jul 2000 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02268149 Apr → Jul 2000 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02265627 Mar → Sep 2000 liver disorder Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02273427 Feb → Mar 2000 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02247375 Jan → May 2000 rheumatoid arthritis Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02265653 Nov → Dec 1999 Boehringer Ingelheim Completed No outcome recorded
Phase 24 trials
Phase 2 NCT02251210 May 2001 → Nov 2002 rheumatoid arthritis Boehringer Ingelheim Completed No outcome recorded
Phase 2 NCT02249247 Apr 2001 → Aug 2002 chronic obstructive pulmonary disease Boehringer Ingelheim Completed No outcome recorded
Phase 2 NCT02249338 Oct 1999 → Apr 2000 chronic obstructive pulmonary disease Boehringer Ingelheim Completed No outcome recorded
Phase 2 NCT02249312 Jul 1999 → Apr 2000 asthma Boehringer Ingelheim Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 18 sources stand behind the page.

FieldValueCited text
Known as AMELUBANT ChEMBL registry synonym — accepted as the source's own label CHEMBL1742420
Known as BIIL 284 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02265302
Known as BIIL 284 BS “Metabolism and Pharmacokinetics of \[14C\]-BIIL 284 BS in Healthy Volunteers” NCT02266550
15

NCT02249312

NCT02249338

NCT02265627

NCT02247375

NCT02249247

NCT02265653

NCT02273427

NCT02265666

NCT02273440

NCT02251210

NCT02273414

NCT02265640

NCT02265679

NCT02268149

NCT02269189

Known as LS-49968 ChEMBL registry synonym — accepted as the source's own label CHEMBL1742420
Action Inhibit “Leukotriene B4 receptor 1 antagonist” CHEMBL1742420
Modality Small molecule CHEMBL1742420
Route Oral “Two Oral Doses of BIIL 284 BS” NCT02247375
Target LTB4R “Leukotriene B4 receptor 1 antagonist” CHEMBL1742420