Drugs / Icosabutate
Trials 7 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 14 trials | ||||||
| Phase 1 | NCT03577275 | Jun → Sep 2018 | hyperlipidemia | NorthSea Therapeutics B.V. | Completed | No outcome recorded |
| Phase 1 | NCT02364635 | Feb → Aug 2015 | — | Pronova BioPharma | Completed | No outcome recorded |
| Phase 1 | NCT02367937 | Aug → Oct 2014 | — | Pronova BioPharma | Completed | No outcome recorded |
| Phase 1 | NCT02373176 | Jul → Sep 2014 | — | Pronova BioPharma | Completed | No outcome recorded |
| Phase 23 trials | ||||||
| Phase 2 | NCT04052516 | Jul 2019 → Feb 2022 | metabolic dysfunction-associated steatohepatitis | NorthSea Therapeutics B.V. | Completed | No outcome recorded |
| Phase 2 | NCT01972178 | Nov 2013 → Jul 2014 | hyperlipidemia | Pronova BioPharma | Terminated | No outcome recorded |
| Phase 2 | NCT01893515 | Jul 2013 → Jul 2014 | hyperlipidemia | Pronova BioPharma | Completed | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 9 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | icosabutate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02367937 ↗ |
| Known as | Icosabutato | ChEMBL registry synonym — accepted as the source's own label CHEMBL3707220 ↗ |
| Known as | NST-4016 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03577275 ↗ |
| Known as | PRB-01022 | “PRB-01022 (icosabutate) (unchanged drug)” NCT02373176 ↗ |
| Known as | PRC-4016 | “[14C]PRC-4016 (Icosabutate)” NCT02373176 ↗ |
| Action | Activate | “icosabutate, a FFAR1/FFAR4 agonist” PMID 39938653 ↗ Feb 2025 |
| Modality | Small molecule | — CHEMBL3707220 ↗ |
| Route | Oral | “PRC-4016, oral administration once daily, capsule” NCT01893515 ↗ |
| Target | FFAR1 | “icosabutate, a FFAR1/FFAR4 agonist” PMID 39938653 ↗ Feb 2025 |
| Target | FFAR4 | “icosabutate, a FFAR1/FFAR4 agonist” PMID 39938653 ↗ Feb 2025 |