Drugs / OBEROTATUG RAVTANSINE
last change Oct 2024 re-read 2 minutes ago

OBEROTATUG RAVTANSINE

also known as OBT076 · MEN1309 · Oberotatug ravtansina

Other / unclassified targets LY75

Developed for
adenoid cystic carcinoma · cancer · metastatic neoplasm · non-Hodgkin lymphoma
Investigated by
Groupe Oncologie Radiotherapie Tete et Cou · Menarini Group · Oxford BioTherapeutics Ltd

Trials 3 · a red edge is where a trial was stopped

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05930951 Nov 2023 → Oct 2024 adenoid cystic carcinoma Groupe Oncologie Radiotherapie Tete et Cou Terminated No outcome recorded
Phase 1 NCT04064359 Jul 2019 → Dec 2026 expected cancer Oxford BioTherapeutics Ltd Recruiting No outcome recorded
Phase 1 NCT03403725 Aug 2017 → Oct 2019 metastatic neoplasm, non-Hodgkin lymphoma Menarini Group Terminated No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as OBEROTATUG RAVTANSINE ChEMBL registry synonym — accepted as the source's own label CHEMBL5314757
Known as MEN1309 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03403725
Known as Oberotatug ravtansina ChEMBL registry synonym — accepted as the source's own label CHEMBL5314757
Known as OBT076 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05930951
1

NCT04064359

Action Deplete “OBT076 is composed of an antibody that targets the CD205 protein on cancer cells and delivers an anti-cancer drug which can kill them.” NCT04064359
Modality Other / unclassified “CD205 Antibody-Drug Conjugate” NCT03403725
Route Intravenous intravenous infusion” NCT03403725
Target LY75 “antibody directed against the CD205/Ly75 antigen (MBH1309)” NCT05930951