Drugs / ES-481
last change Jun 2026 re-read 3 minutes ago

ES-481

Developed for
epilepsy · essential tremor
Investigated by
ES Therapeutics Australia Pty Ltd

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT05234762 Nov 2021 → Dec 2023 essential tremor ES Therapeutics Australia Pty Ltd Unknown No outcome recorded
Phase 2 NCT04737174 Mar → Oct 2021 epilepsy ES Therapeutics Australia Pty Ltd Withdrawn No outcome recorded
Phase 2 NCT04714996 Oct 2020 → Dec 2023 epilepsy ES Therapeutics Australia Pty Ltd Unknown Mixed

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as ES-481 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04737174 ↗
2

NCT04714996 ↗

NCT05234762 ↗

Action Inhibit “novel potent and selective antagonist of TARP-y8-dependent AMPA receptors” PMID 42312676 ↗ Jun 2026
Route Oral “Administered as 25 mg oral gelatin capsules” NCT04737174 ↗