Drugs / AZD6280
last change Mar 2009 re-read 9 days ago

AZD6280

Small molecule targets GABRA2, GABRA3 via activation

Investigated by
AstraZeneca

Trials 4

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00824057 Jan → Mar 2009 — AstraZeneca Completed No outcome recorded
Phase 1 NCT00750802 Sep → Dec 2008 — AstraZeneca Completed No outcome recorded
Phase 1 NCT00681317 Mar → Jul 2008 — AstraZeneca Completed No outcome recorded
Phase 1 NCT00681746 Feb → Sep 2008 anxiety AstraZeneca Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as AZD6280 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00681317 ↗
3

NCT00750802 ↗

NCT00681746 ↗

NCT00824057 ↗

Action Activate “GABA receptor alpha-3 subunit positive allosteric modulator” CHEMBL1783256 ↗
1

“GABA receptor alpha-2 subunit positive allosteric modulator” CHEMBL1783256 ↗

Modality Small molecule — CHEMBL1783256 ↗
Route Oral “oral” NCT00681317 ↗
Target GABRA2 “GABA receptor alpha-2 subunit positive allosteric modulator” CHEMBL1783256 ↗
Target GABRA3 “GABA receptor alpha-3 subunit positive allosteric modulator” CHEMBL1783256 ↗