Drugs / AZD6280
last change Mar 2009 re-read 2 minutes ago

AZD6280

Small molecule targets GABRA2, GABRA3 via activation

Investigated by
AstraZeneca

Trials 4 · a red edge is where a trial was stopped

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00824057 Jan → Mar 2009 AstraZeneca Completed No outcome recorded
Phase 1 NCT00750802 Sep → Dec 2008 AstraZeneca Completed No outcome recorded
Phase 1 NCT00681317 Mar → Jul 2008 AstraZeneca Completed No outcome recorded
Phase 1 NCT00681746 Feb → Sep 2008 anxiety AstraZeneca Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as AZD6280 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00750802
3

NCT00681317

NCT00681746

NCT00824057

Action Activate “GABA receptor alpha-3 subunit positive allosteric modulator” CHEMBL1783256
1

“GABA receptor alpha-2 subunit positive allosteric modulator” CHEMBL1783256

Modality Small molecule CHEMBL1783256
Route Oral oralNCT00681317
Target GABRA2 “GABA receptor alpha-2 subunit positive allosteric modulator” CHEMBL1783256
Target GABRA3 “GABA receptor alpha-3 subunit positive allosteric modulator” CHEMBL1783256