Drugs / Birtamimab
Birtamimab
Trials 7 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT01707264 | Apr 2013 → Aug 2016 | AL amyloidosis | Prothena Biosciences Ltd. | Completed | No outcome recorded |
| Phase 24 trials | ||||||
| Phase 2 | NCT03168906 | Jul 2017 → Apr 2018 | AL amyloidosis | Tufts Medical Center | Terminated | No outcome recorded |
| Phase 2 | NCT03154047 | Jun 2017 → May 2018 | AL amyloidosis | Prothena Biosciences Ltd. | Terminated | No outcome recorded |
| Phase 2 | NCT02632786 | Mar 2016 → Mar 2018 | AL amyloidosis | Prothena Biosciences Ltd. | Completed | No outcome recorded |
| Phase 2 | NCT02613182 | Feb 2016 → May 2018 | AL amyloidosis | Prothena Biosciences Ltd. | Terminated | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT04973137 | Aug 2021 → Apr 2025 | AL amyloidosis | Prothena Biosciences Ltd. | Terminated | No outcome recorded |
| Phase 3 | NCT02312206 | Feb 2015 → May 2018 | primary systemic amyloidosis | Prothena Biosciences Ltd. | Terminated | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 9 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Birtamimab | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04973137 ↗ |
| Known as | ELT1-01 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3833345 ↗ |
| Known as | Hu2A4 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3833345 ↗ |
| Known as | NEOD001 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02613182 ↗ |
| Modality | Monoclonal antibody | “Monoclonal antibody administered by intravenous infusion every 28 days.” NCT01707264 ↗ |
| Route | Intravenous | “Patients who had completed at least one previous anti-plasma cell-directed therapy, had partial hematologic response or better, and had persistent organ dysfunction received...” PMID 26858336 ↗ Feb 2016 |