Drugs / Vopratelimab
last change Apr 2024 re-read 3 minutes ago

Vopratelimab

Monoclonal antibody targets ICOS via activation

Developed for
cancer · non-small cell lung carcinoma
Investigated by
Jounce Therapeutics, Inc.

Trials 4

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/22 trials
Phase 1/2 NCT04319224 Mar 2020 → Jan 2023 cancer Jounce Therapeutics, Inc. Terminated No outcome recorded Stop: Business
Phase 1/2 NCT02904226 Aug 2016 → Jul 2020 cancer Jounce Therapeutics, Inc. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT04549025 Oct 2020 → Apr 2024 non-small cell lung carcinoma Jounce Therapeutics, Inc. Terminated No outcome recorded Stop: Enrollment
Phase 2 NCT03989362 Jun 2019 → Mar 2022 cancer Jounce Therapeutics, Inc. Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Vopratelimab ClinicalTrials.gov intervention name — accepted as the source's own label NCT04319224 ↗
2

NCT04549025 ↗

NCT03989362 ↗

Known as Anti-icos agonist mab jtx-2011 ChEMBL registry synonym — accepted as the source's own label CHEMBL4298004 ↗
Known as JTX-2011 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02904226 ↗
Action Activate “JTX-2011 is an agonist monoclonal antibody” NCT02904226 ↗
Modality Monoclonal antibody “JTX-2011 is an agonist monoclonal antibody” NCT02904226 ↗
Route Intravenous “by intravenous (IV) infusion” NCT02904226 ↗
Target ICOS “specifically binds to the Inducible CO-Stimulator of T cells (ICOS)” NCT02904226 ↗