Drugs / Liarozole
Liarozole
also known as
Liarozol · LIAROZOLE FUMARATE · Liarozole hcl · LIAROZOLE HYDROCHLORIDE · Liazal · R 75251 · R 85246
Trials 1
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2/3 | NCT00282724 | Jan 2006 → Apr 2007 | lamellar ichthyosis | Stiefel, a GSK Company | Completed | Missed primary |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Liarozole | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00282724 ↗ |
| Known as | Liarozol | ChEMBL registry synonym — accepted as the source's own label CHEMBL389433 ↗ |
| Known as | LIAROZOLE FUMARATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL389433 ↗ |
| Known as | Liarozole hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL389433 ↗ |
| Known as | LIAROZOLE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL389433 ↗ |
| Known as | Liazal | ChEMBL registry synonym — accepted as the source's own label CHEMBL389433 ↗ |
| Known as | R 75251 | ChEMBL registry synonym — accepted as the source's own label CHEMBL389433 ↗ |
| Known as | R 85246 | ChEMBL registry synonym — accepted as the source's own label CHEMBL389433 ↗ |
| Action | Inhibit | “The primary activity of liarozole is considered to be the inhibition of the degradation of a substance called retinoic acid” NCT00282724 ↗ |
| Modality | Small molecule | — CHEMBL389433 ↗ |
| Route | Oral | “Patients aged ≥ 14 years with moderate/severe lamellar ichthyosis [Investigator's Global Assessment (IGA) score ≥ 3] were randomized 3 : 3 : 1 to receive oral liarozole (75 or...” PMID 24102348 ↗ Jan 2014 |