Drugs / TILREKIMIG
last change Mar 2026 re-read 3 minutes ago

TILREKIMIG

also known as PF-07275315

Monoclonal antibody

Developed for
asthma · atopic eczema · chronic obstructive pulmonary disease
Investigated by
Pfizer

Trials 5

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT06675188 Jan → Jul 2025 — Pfizer Completed No outcome recorded
Phase 1 NCT05411588 Jun 2022 → May 2024 — Pfizer Completed No outcome recorded
Phase 22 trials
Phase 2 NCT06977581 May 2025 → Mar 2027 expected asthma Pfizer Recruiting No outcome recorded
Phase 2 NCT05995964 Aug 2023 → Oct 2026 expected atopic eczema Pfizer Recruiting No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT07363694 Feb 2026 → Oct 2030 expected chronic obstructive pulmonary disease Pfizer Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2026-03-09 Pfizer Results Pfizer’s Phase 2 Study of Trispecific Antibody Positive in Moderate to Severe Atopic Dermatitis pfizer.com ↗
The study met its primary efficacy endpoint, demonstrating a statistically significant increase in the percentage of participants achieving EASI-75* (≥ 75% reduction in the Eczema Area and Severity Index) at Week 16, compared to placebo.

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as TILREKIMIG ChEMBL registry synonym — accepted as the source's own label CHEMBL6068474 ↗
Known as PF-07275315 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06675188 ↗
4

NCT05995964 ↗

NCT07363694 ↗

NCT06977581 ↗

NCT05411588 ↗

Modality Monoclonal antibody — CHEMBL6068474 ↗
Route Intravenous “SINGLE AND MULTIPLE INTRAVENOUS AND SUBCUTANEOUS DOSES OF PF-07275315” NCT05411588 ↗
Route Subcutaneous “SINGLE AND MULTIPLE INTRAVENOUS AND SUBCUTANEOUS DOSES OF PF-07275315” NCT05411588 ↗