Drugs / Anti-MAGE-A3-DP4 T Cell Receptor (TCR) Peripheral Blood Lymphocytes (PBL)
last change Mar 2021 re-read 2 minutes ago

Anti-MAGE-A3-DP4 T Cell Receptor (TCR) Peripheral Blood Lymphocytes (PBL)

Cell therapy

Developed for
breast cancer · cervical cancer · kidney cancer · melanoma · urothelial carcinoma
Investigated by
National Cancer Institute (NCI)

Trials 1 · a red edge is where a trial was stopped

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT02111850 Feb 2014 → Mar 2021 breast cancer, cervical cancer, kidney cancer, melanoma +1 National Cancer Institute (NCI) Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Anti-MAGE-A3-DP4 T Cell Receptor (TCR) Peripheral Blood Lymphocytes (PBL) ClinicalTrials.gov intervention name — accepted as the source's own label NCT02111850
Action Deplete “genetically modifying these specific cells with a type of virus (retrovirus) to attack only the tumor cells” NCT02111850
Modality Cell therapy “ex vivo tumor reactive, TCR gene-transduced peripheral blood mononuclear cells (PBMC)” NCT02111850
Route Intravenous “Day 0: cells will be infused intravenously (i.v.) on the Patient Care Unit over 20 to 30 minutes” NCT02111850