Drugs / Griffithsin
last change Jan 2022 re-read 3 minutes ago

Griffithsin

also known as GRFT · PC-6500
Developed for
HIV infectious disease
Investigated by
Population Council

Trials 1

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02875119 Oct 2017 → Jul 2018 HIV infectious disease Population Council Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Griffithsin ClinicalTrials.gov intervention name — accepted as the source's own label NCT02875119 ↗
Known as GRFT “Griffithsin (GRFT) is a non-ARV lectin with potent anti-HIV activity.” PMID 35051209 ↗ Jan 2022
Known as PC-6500 “A Phase 1 Trial to Evaluate the Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of PC-6500 (Griffithsin [GRFT] in a Carrageenan Gel) in Healthy Women” NCT02875119 ↗
Action Inhibit “GRFT inhibited entry of pseudo-particles typed with ANDV envelope glycoprotein into host cells” PMID 33251157 ↗ Nov 2020
Route Other “after vaginal administration” PMID 35051209 ↗ Jan 2022