Drugs / CS1003
last change Jun 2025 re-read 2 minutes ago

CS1003

Monoclonal antibody targets PDCD1 via inhibition

Developed for
cancer · cancer of unknown primary site · hepatocellular carcinoma · lymphoma
Investigated by
CStone Pharmaceuticals

Trials 4 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT03809767 Oct 2018 → Aug 2021 cancer, lymphoma CStone Pharmaceuticals Completed No outcome recorded
Phase 1 NCT03475251 May 2018 → May 2021 cancer of unknown primary site CStone Pharmaceuticals Completed No outcome recorded
Phase 1 NCT03523819 Apr 2018 → Jan 2022 cancer CStone Pharmaceuticals Completed No outcome recorded
Phase 31 trial
Phase 3 NCT04194775 Dec 2019 → Jun 2025 overdue hepatocellular carcinoma CStone Pharmaceuticals Active not recruiting No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as CS1003 “Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma” NCT04194775
3

NCT03523819

NCT03809767

NCT03475251

Known as Antibody cs1003 ChEMBL registry synonym — accepted as the source's own label CHEMBL4594536
Known as Nofazinlimab ClinicalTrials.gov intervention name — accepted as the source's own label NCT04194775
Known as Recombinant pd-1 mab cs1003 ChEMBL registry synonym — accepted as the source's own label CHEMBL4594536
Action Inhibit “Programmed cell death protein 1 inhibitor” CHEMBL4594536
1

“Anti-PD-1” NCT03523819

Modality Monoclonal antibody “Anti-PD-1 Monoclonal Antibody CS1003” NCT03475251
Route Intravenous “CS1003 to be intravenously administered at the dose level determined during the dose escalation part” NCT03475251
Target PDCD1 “Programmed cell death protein 1 inhibitor” CHEMBL4594536