Drugs / recombinant tissue-type plasminogen activator
last change Dec 2020 re-read 3 minutes ago

recombinant tissue-type plasminogen activator

also known as r-tPA

Protein / enzyme biologic

Developed for
pulmonary embolism
Investigated by
Thrombolex, Inc.

Trials 1

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03927508 Mar → Dec 2019 pulmonary embolism Thrombolex, Inc. Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as recombinant tissue-type plasminogen activator “The total dose of r-tPA (recombinant tissue-type plasminogen activator) was 14 mgs in bilateral PE and 12 mgs in unilateral PE over 8 hours delivered via the expanded BEC.” PMID 33356383 ↗ Dec 2020
Known as r-tPA ClinicalTrials.gov intervention name — accepted as the source's own label NCT03927508 ↗
Modality Protein / enzyme biologic “The total dose of r-tPA (recombinant tissue-type plasminogen activator) was 14 mgs in bilateral PE and 12 mgs in unilateral PE over 8 hours delivered via the expanded BEC.” PMID 33356383 ↗ Dec 2020
Route Other “localized infusion of therapeutic agents into the pulmonary artery” NCT03927508 ↗