Drugs / VONLEROLIZUMAB
last change Nov 2019 re-read 3 minutes ago

VONLEROLIZUMAB

also known as MOXR0916 · Pogalizumab · R0-7021608 · RG-7888 · RO7021608

Monoclonal antibody

Developed for
neoplasm · urothelial carcinoma
Investigated by
Genentech, Inc.

Trials 3

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02410512 Apr 2015 → Nov 2019 neoplasm Genentech, Inc. Completed No outcome recorded
Phase 1 NCT02219724 Aug 2014 → Jul 2017 neoplasm Genentech, Inc. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT03029832 Apr 2017 → Apr 2018 urothelial carcinoma Genentech, Inc. Terminated No outcome recorded Stop: Enrollment

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2016-05-02 Genentech, Inc. Results Genentech Highlights Personalized Medicines and Cancer Immunotherapies at 2016 American Society of Clinical Oncology (ASCO) Annual Meeting gene.com ↗
Early results for atezolizumab in combination with targeted medicines and the investigational cancer immunotherapy MOXR0916, an OX40 agonist

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as VONLEROLIZUMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL3990022 ↗
Known as MOXR0916 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02410512 ↗
2

NCT02219724 ↗

NCT03029832 ↗

Known as Pogalizumab ChEMBL registry synonym — accepted as the source's own label CHEMBL3990022 ↗
Known as R0-7021608 ChEMBL registry synonym — accepted as the source's own label CHEMBL3990022 ↗
Known as RG-7888 ChEMBL registry synonym — accepted as the source's own label CHEMBL3990022 ↗
Known as RO7021608 ChEMBL registry synonym — accepted as the source's own label CHEMBL3990022 ↗
Action Activate “humanized agonist anti-OX40 monoclonal antibody” NCT02410512 ↗
Modality Monoclonal antibody “humanized agonist anti-OX40 monoclonal antibody” NCT02410512 ↗
Route Intravenous “administered as intravenous infusion” NCT02219724 ↗