Drugs / IMC-CS4
last change Mar 2026 re-read 3 minutes ago

IMC-CS4

targets CSF1R via inhibition

Developed for
malignant pancreatic neoplasm · neoplasm
Investigated by
Eli Lilly and Company · Merck Sharp & Dohme LLC · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Trials 2

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial · 1 met primary
Phase 0 NCT03153410 Sep 2018 → Mar 2022 malignant pancreatic neoplasm Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Completed Met primary
Phase 11 trial
Phase 1 NCT01346358 Jun 2011 → May 2018 neoplasm Eli Lilly and Company Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as IMC-CS4 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03153410 ↗
1

NCT01346358 ↗

Action Inhibit “CSF1 receptor blockade (IMC-CS4)” PMID 41878443 ↗ Mar 2026
Route Intravenous “intravenous (IV) infusion” NCT03153410 ↗
Target CSF1R “anti-CSF1R agent IMC-CS4” PMID 41878443 ↗ Mar 2026