Drugs / ELUBRIXIN
last change Sep 2012 re-read 9 days ago

ELUBRIXIN

Small molecule targets CXCR2

Developed for
cystic fibrosis · ulcerative colitis
Investigated by
GlaxoSmithKline

Trials 6

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT00615576 Mar → Jul 2008 chronic obstructive pulmonary disease GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00605761 Feb → Dec 2008 cystic fibrosis GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00551811 Oct 2007 → Jul 2008 chronic obstructive pulmonary disease GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00504439 Jun → Sep 2007 chronic obstructive pulmonary disease GlaxoSmithKline Completed No outcome recorded
Phase 22 trials
Phase 2 NCT00903201 Sep 2009 → Dec 2010 cystic fibrosis GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT00748410 Jan → Dec 2009 ulcerative colitis GlaxoSmithKline Terminated No outcome recorded

Evidence & citations 11 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as ELUBRIXIN ChEMBL registry synonym — accepted as the source's own label CHEMBL2178579 ↗
Known as Elubrixin tosilate ChEMBL registry synonym — accepted as the source's own label CHEMBL2178579 ↗
Known as ELUBRIXIN TOSYLATE ChEMBL registry synonym — accepted as the source's own label CHEMBL2178579 ↗
Known as Elubrixina ChEMBL registry synonym — accepted as the source's own label CHEMBL2178579 ↗
Known as Elubrixine ChEMBL registry synonym — accepted as the source's own label CHEMBL2178579 ↗
Known as SB-656933 “The objective of this study was to evaluate the safety, tolerability and pharmacodynamics of SB-656933, an oral CXCR2 antagonist.” PMID 22995323 ↗ Sep 2012
4

NCT00748410 ↗

NCT00903201 ↗

NCT00605761 ↗

NCT00615576 ↗

Known as SB-656933-AAA ClinicalTrials.gov intervention name — accepted as the source's own label NCT00504439 ↗
1

NCT00551811 ↗

Known as SB-656933-AAF ChEMBL registry synonym — accepted as the source's own label CHEMBL2178579 ↗
Modality Small molecule — CHEMBL2178579 ↗
Route Oral “The tablets will be administered orally.” NCT00504439 ↗
Target CXCR2 “SB-656933, an oral CXCR2 antagonist” PMID 22995323 ↗ Sep 2012