Drugs / AZD5991
last change Jun 2023 re-read 2 minutes ago

AZD5991

Small molecule targets MCL1 via inhibition

Developed for
acute myeloid leukemia
Investigated by
AstraZeneca · Beat AML, LLC

Trials 2 · a red edge is where a trial was stopped

2017201820192020202120222023202420252026202720282029
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03218683 Aug 2017 → Oct 2021 acute myeloid leukemia AstraZeneca Terminated No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT03013998 Nov 2016 → Dec 2028 expected acute myeloid leukemia Beat AML, LLC Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as AZD5991 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03013998
1

NCT03218683

Action Inhibit “Mcl-1 inhibitor AZD5991” PMID 37380821 Jun 2023
Modality Small molecule CHEMBL4297482
Route Intravenous “150 mg, IV, on days 1, 4, 8, 11, 15, and 18” NCT03013998
Target MCL1 “Mcl-1 inhibitor AZD5991” PMID 37380821 Jun 2023