Drugs / pIRS2-phosphopeptide
last change May 2020 re-read 2 minutes ago

pIRS2-phosphopeptide

also known as pIRS2 · pIRS21097-1105

Vaccine targets IRS2

Developed for
melanoma
Investigated by
Craig L Slingluff, Jr

Trials 1 · a red edge is where a trial was stopped

201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01846143 May 2013 → Jun 2015 melanoma Craig L Slingluff, Jr Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as pIRS2-phosphopeptide ClinicalTrials.gov intervention name — accepted as the source's own label NCT01846143
Known as pIRS2 “an HLA-A*0201-restricted phosphopeptide from insulin receptor substrate 2 (pIRS2)” PMID 32385144 May 2020
Known as pIRS21097-1105 “The pIRS21097-1105 peptide was identified by mass spectrometry from human hepatocellular carcinoma tumors” PMID 32385144 May 2020
Modality Vaccine “a novel immunotherapic vaccine comprising either or both of these phosphorylated peptides” PMID 32385144 May 2020
Route Subcutaneous “The peptides will be administered subcutaneously (0.5 ml) and intradermally (0.5 ml) in Montanide ISA-51 VG adjuvant” NCT01846143
Target IRS2 “an HLA-A*0201-restricted phosphopeptide from insulin receptor substrate 2 (pIRS2)” PMID 32385144 May 2020