Drugs / CC-90011
last change Jul 2024 re-read 2 minutes ago

CC-90011

Small molecule

Developed for
myeloid leukemia · neoplasm · non-Hodgkin lymphoma · prostate neoplasm · small cell lung carcinoma
Investigated by
Celgene Corporation

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT04748848 Oct 2021 → Mar 2022 myeloid leukemia Celgene Corporation Terminated No outcome recorded
Phase 1 NCT04628988 Jul 2021 → May 2023 prostate neoplasm Celgene Corporation Completed No outcome recorded
Phase 1 NCT03850067 Mar 2019 → Jul 2024 small cell lung carcinoma Celgene Corporation Completed No outcome recorded
Phase 1 NCT02875223 Aug 2016 → Mar 2024 non-Hodgkin lymphoma Celgene Corporation Terminated No outcome recorded
Phase 21 trial
Phase 2 NCT04350463 Jul 2020 → Dec 2023 neoplasm Celgene Corporation Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as CC-90011 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03850067
4

NCT04748848

NCT04628988

NCT04350463

NCT02875223

Known as Pulrodemstat benzenesulfonate ChEMBL registry synonym — accepted as the source's own label CHEMBL4651180
Known as PULRODEMSTAT BESILATE ChEMBL registry synonym — accepted as the source's own label CHEMBL4651180
Action Inhibit “CC-90011 is an oral, potent, selective, reversible inhibitor of lysine-specific demethylase 1 (LSD1)” PMID 35737639 Jun 2022
Modality Small molecule CHEMBL4651180
Route Oral “explore escalating oral doses of CC-90011” NCT02875223