Drugs / Pipamperone
Pipamperone
also known as
PIP · Floropipamide · NSC-759178 · Pipamperona · Pipamperone Hydrochloride · Pipaneperone · R 3345
Trials 2
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 21 trial | ||||||
| Phase 2 | NCT01450514 | Mar → Nov 2012 | schizoaffective disorder, schizophrenia | PharmaNeuroBoost N.V. | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT02374567 | Jan 2015 → Jun 2017 | anxiety disorder, dementia, depressive disorder, schizophrenia +1 | Hannover Medical School | Terminated | No outcome recorded |
| Comparator or background therapy3 trials | ||||||
| Phase 2 | NCT01323205 Background | May 2011 → Nov 2012 | schizophrenia | Janssen Research & Development, LLC | Completed | No outcome recorded |
| Phase 2 | NCT00672659 Comparator | Feb 2008 → Jan 2009 | major depressive disorder | PharmaNeuroBoost N.V. | Completed | No outcome recorded |
| Phase 3 | NCT01312922 Comparator | Sep 2011 → Nov 2012 | major depressive disorder | PharmaNeuroBoost N.V. | Completed | No outcome recorded |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Pipamperone | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02374567 ↗ |
| Known as | Floropipamide | ChEMBL registry synonym — accepted as the source's own label CHEMBL440294 ↗ |
| Known as | NSC-759178 | ChEMBL registry synonym — accepted as the source's own label CHEMBL440294 ↗ |
| Known as | PIP | “This Phase I/IIa Proof-of-Concept (PoC) trial is designed to assess the effect of adding a single and repeated low dose (15mg/d) of pipamperone (PIP) for 6 weeks to stable...” NCT01450514 ↗1“Pipamperone/Citalopram (PNB01) Versus Citalopram (CIT) and Versus Pipamperone (PIP) in Major Depressive Disorder (MDD)” NCT01312922 ↗ |
| Known as | Pipamperona | ChEMBL registry synonym — accepted as the source's own label CHEMBL440294 ↗ |
| Known as | Pipamperone Hydrochloride | “Regular antipsychotic medications (Risperidone, Olanzapine, Clozapine, Amisulpride, Quetiapine, Paliperidone, Aripiprazole, Haloperidol, Levomepromazine, Zuclopenthixol...” NCT01323205 ↗ |
| Known as | Pipaneperone | ChEMBL registry synonym — accepted as the source's own label CHEMBL440294 ↗ |
| Known as | R 3345 | ChEMBL registry synonym — accepted as the source's own label CHEMBL440294 ↗ |
| Action | Inhibit | “Pipamperone acts as a highly selective 5-HT2A/D4 antagonist” PMID 21349239 ↗ Feb 2011 |
| Modality | Small molecule | — CHEMBL440294 ↗ |
| Route | Oral | “15 mg PIP once daily per os on top of continued stable treatment with RIS or PAL” NCT01450514 ↗ |