Drugs / Abequolixron
last change Feb 2025 re-read 2 minutes ago

Abequolixron

also known as RGX-104 · SB-742881

Small molecule

Developed for
non-small cell lung carcinoma · endometrial cancer
Investigated by
AstraZeneca · Inspirna, Inc. · Rgenix, Inc. · UNC Lineberger Comprehensive Cancer Center

Trials 2 · a red edge is where a trial was stopped

2017201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05911308 Apr → Oct 2024 non-small cell lung carcinoma UNC Lineberger Comprehensive Cancer Center Terminated No outcome recorded
Phase 1 NCT02922764 Nov 2016 → Jan 2025 endometrial cancer, non-small cell lung carcinoma Inspirna, Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Abequolixron ClinicalTrials.gov intervention name — accepted as the source's own label NCT05911308
Known as RGX-104 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02922764
Known as SB-742881 ChEMBL registry synonym — accepted as the source's own label CHEMBL573677
Action Activate “RGX-104 activates LXR” NCT02922764
Modality Small molecule “RGX-104, an oral small molecule targeting the liver X receptor (LXR)” NCT02922764
1

CHEMBL573677

Route Oral oral small molecule targeting the liver X receptor (LXR)” NCT02922764