Drugs / ECHOTHIOPHATE
last change Jun 2026 re-read 3 minutes ago

ECHOTHIOPHATE

Small molecule targets ACHE via inhibition

Developed for
amblyopia · myopia
Investigated by
Danbury Eye Physicians & Surgeons, PC · Fera Pharmaceuticals, LLC · University of Oklahoma

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) PHOSPHOLINE IODIDE — 1960-06-27 fda.gov ↗

Trials 2

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT07554131 Jun → Dec 2026 expected amblyopia University of Oklahoma Not yet recruiting No outcome recorded
Phase 41 trial
Phase 4 NCT02544529 Jun 2016 myopia Danbury Eye Physicians & Surgeons, PC Withdrawn No outcome recorded Stop: Business

Evidence & citations 16 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as ECHOTHIOPHATE ChEMBL registry synonym — accepted as the source's own label CHEMBL1201341 ↗
Known as 217-MI ChEMBL registry synonym — accepted as the source's own label CHEMBL1201341 ↗
Known as Echodide ChEMBL registry synonym — accepted as the source's own label CHEMBL1201341 ↗
Known as Echothiophate cation ChEMBL registry synonym — accepted as the source's own label CHEMBL1201341 ↗
Known as Echothiophate Iodide ClinicalTrials.gov intervention name — accepted as the source's own label NCT07554131 ↗
1

NCT02544529 ↗

Known as Echothiophate ion ChEMBL registry synonym — accepted as the source's own label CHEMBL1201341 ↗
Known as Ecothiopate ChEMBL registry synonym — accepted as the source's own label CHEMBL1201341 ↗
Known as Ecothiopate cation ChEMBL registry synonym — accepted as the source's own label CHEMBL1201341 ↗
Known as Ecothiopate iodide ChEMBL registry synonym — accepted as the source's own label CHEMBL1201341 ↗
Known as Iodure d'ecothiopate ChEMBL registry synonym — accepted as the source's own label CHEMBL1201341 ↗
Known as Ioduro de ecotiopato ChEMBL registry synonym — accepted as the source's own label CHEMBL1201341 ↗
Known as Phospholine Iodide “echothiophate iodide (Phospholine Iodide) can help treat children with refractory amblyopia” NCT07554131 ↗
Action Inhibit “Acetylcholinesterase inhibitor” CHEMBL1201341 ↗
Modality Small molecule — CHEMBL1201341 ↗
Route Topical “echothiophate iodide eye drops in addition to standard atropine therapy” NCT07554131 ↗
Target ACHE “Acetylcholinesterase inhibitor” CHEMBL1201341 ↗