Drugs / Bradanicline
last change May 2019 re-read 3 minutes ago

Bradanicline

Small molecule targets CHRNA7 via activation

Developed for
schizophrenia · Alzheimer disease · respiratory system disorder · attention deficit-hyperactivity disorder
Investigated by
Targacept Inc. · Attenua, Inc.

Trials 4

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01254448 Sep 2010 → Mar 2011 Alzheimer disease Targacept Inc. Completed No outcome recorded
Phase 23 trials
Phase 2 NCT03622216 Nov 2018 → May 2019 respiratory system disorder Attenua, Inc. Completed No outcome recorded
Phase 2 NCT01488929 Dec 2011 → Nov 2013 schizophrenia Targacept Inc. Completed No outcome recorded
Phase 2 NCT01003379 Oct 2009 → Nov 2010 schizophrenia Targacept Inc. Completed No outcome recorded
Comparator or background therapy1 trial
Phase 2 NCT01124708 Comparator May 2010 → Feb 2011 attention deficit-hyperactivity disorder Targacept Inc. Completed No outcome recorded

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Bradanicline ClinicalTrials.gov intervention name — accepted as the source's own label NCT03622216 ↗
Known as ATA-101 ChEMBL registry synonym — accepted as the source's own label CHEMBL1258006 ↗
Known as Bradaniclina ChEMBL registry synonym — accepted as the source's own label CHEMBL1258006 ↗
Known as BRADANICLINE HYDROCHLORIDE ChEMBL registry synonym — accepted as the source's own label CHEMBL1258006 ↗
Known as TC-5619 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01003379 ↗
3

NCT01124708 ↗

NCT01488929 ↗

NCT01254448 ↗

Known as TC-5619-023 ChEMBL registry synonym — accepted as the source's own label CHEMBL1258006 ↗
Action Activate “Neuronal acetylcholine receptor protein alpha-7 subunit agonist” CHEMBL1258006 ↗
Modality Small molecule — CHEMBL1258006 ↗
Route Oral “one capsule once daily p.o.” NCT01124708 ↗
Target CHRNA7 “Neuronal acetylcholine receptor protein alpha-7 subunit agonist” CHEMBL1258006 ↗