Arformoterol
Small molecule targets ADRB2 via activation
Regulatory milestones approvals, filings & regulatory actions · 2 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | BROVANA | — | 2014-02-27 | fda.gov ↗ |
| Approved | US (FDA) | BROVANA | — | 2006-10-06 | fda.gov ↗ |
Trials 17 · a red edge is where a trial was stopped
Also used as a comparator or background therapy in 3 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 42 trials | ||||||
| Phase 4 | NCT00754546 Comparator | Aug 2008 → May 2009 | chronic obstructive pulmonary disease | Dartmouth-Hitchcock Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT00424528 Comparator | Dec 2006 → Oct 2007 | bronchitis, pulmonary emphysema | Sumitomo Pharma America, Inc. | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT00846287 Comparator | Nov 2008 → Apr 2011 | chronic obstructive pulmonary disease | University of Massachusetts, Worcester | Completed | No outcome recorded |
Evidence & citations 12 cited values
Every value below carries the sentence it was read from. 22 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | arformoterol | “Budesonide/Arformoterol dry powder inhaler, 3 inhalations b.i.d at 3 days and 2 inhalations b.i.d at 11 days” NCT05055414 ↗18“Subjects will receive the drug arformoterol prior to scanning” NCT00846287 ↗ |
| Known as | ARFORMOTEROL FUMARATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1363 ↗ |
| Known as | Arformoterol tartrate | “Arformoterol tartrate inhalation solution 15 mcg (BROVANA) will be administered BID (morning and evening, approximately 12 hours between doses) using a standard jet nebulizer...” NCT02275481 ↗6“Arformoterol tartrate 15 µg/2ml (Brovana) nebulized via PARI-LC Plus® nebulizer with a mouthpiece, connected to a PRONEB® Ultra compressor.” NCT01361984 ↗ “Arformoterol tartrate (arformoterol, 15 μg bid) is a nebulized long-acting β2-agonist approved for maintenance treatment of COPD.” PMID 25451347 ↗ Dec 2014 “Arformoterol tartrate inhalation solution 15 mcg twice daily and placebo inhalation powder once daily.” NCT00424528 ↗ “Arformoterol Tartrate Inhalation Solution” NCT00571428 ↗ “Arformoterol tartrate inhalation solution” NCT00691405 ↗ “Arformoterol tartrate inhalation solution” NCT00250679 ↗ |
| Known as | Brovana | “Arformoterol (Brovana)” NCT00773786 ↗ |
| Known as | Brovana, (R,R)-formoterol | “Brovana, (R,R)-formoterol” NCT00685529 ↗ |
| Known as | Formoterol r,r-form | ChEMBL registry synonym — accepted as the source's own label CHEMBL1363 ↗ |
| Known as | Formoterol r,r-form l-tartrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL1363 ↗ |
| Known as | RR formoterol | “arformoterol (RR formoterol)” NCT00819637 ↗ |
| Action | Activate | “Beta-2 adrenergic receptor agonist” CHEMBL1363 ↗ |
| Modality | Small molecule | — CHEMBL1363 ↗ |
| Route | Inhaled | “arformoterol tartrate inhalation solution” NCT00064402 ↗ |
| Target | ADRB2 | “Beta-2 adrenergic receptor agonist” CHEMBL1363 ↗ |