Drugs / JNJ-74699157
last change Jul 2022 re-read 3 minutes ago

JNJ-74699157

targets KRAS via inhibition

Developed for
colorectal cancer · non-small cell lung carcinoma
Investigated by
Janssen Research & Development, LLC

Trials 1

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04006301 Jul 2019 → Jul 2020 colorectal cancer, non-small cell lung carcinoma Janssen Research & Development, LLC Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as JNJ-74699157 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04006301 ↗
Action Inhibit “an oral, selective, covalent inhibitor of the KRAS G12C isoform” PMID 35325211 ↗ Jul 2022
Route Oral “Participants will receive JNJ-74699157 orally.” NCT04006301 ↗
Target KRAS “inhibitor of the KRAS G12C isoform” PMID 35325211 ↗ Jul 2022