Drugs / ABBV-176
last change Jun 2020 re-read 3 minutes ago

ABBV-176

Other / unclassified

Investigated by
AbbVie

Trials 1

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03145909 Jul 2017 → Nov 2018 — AbbVie Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as ABBV-176 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03145909 ↗
Action Deplete “conjugated to a highly potent, cytotoxic cross-linking pyrrolobenzodiazepine dimer (PBD; SGD-1882) targeting the prolactin receptor (PRLR)” PMID 32524319 ↗ Jun 2020
Modality Other / unclassified “ABBV-176 is an antibody-drug conjugate composed of the humanized antibody h16f (PR-1594804) conjugated to a highly potent, cytotoxic cross-linking pyrrolobenzodiazepine dimer...” PMID 32524319 ↗ Jun 2020
Route Intravenous “Intravenous infusion” NCT03145909 ↗