Drugs / Quilizumab
last change Nov 2014 re-read 3 minutes ago

Quilizumab

also known as MEMP1972A · ANTI-M1 · Anti-M1 prime · MEP-1972A · RG-7449

Monoclonal antibody targets IGHE via inhibition

Developed for
asthma · allergic rhinitis · urticaria
Investigated by
Genentech, Inc.

Trials 3

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01160861 Jul 2010 → Apr 2011 allergic rhinitis Genentech, Inc. Completed No outcome recorded
Phase 22 trials · 1 missed
Phase 2 NCT01582503 Apr 2012 → May 2014 asthma Genentech, Inc. Completed Missed primary
Phase 2 NCT01196039 Dec 2010 → Aug 2011 asthma Genentech, Inc. Completed No outcome recorded
Comparator or background therapy1 trial
Phase 2 NCT01987947 Comparator Dec 2013 → Oct 2014 urticaria Genentech, Inc. Completed No outcome recorded

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Quilizumab ClinicalTrials.gov intervention name — accepted as the source's own label NCT01987947 ↗
Known as ANTI-M1 ChEMBL registry synonym — accepted as the source's own label CHEMBL2109456 ↗
Known as Anti-M1 prime ChEMBL registry synonym — accepted as the source's own label CHEMBL2109456 ↗
Known as MEMP1972A ClinicalTrials.gov intervention name — accepted as the source's own label NCT01582503 ↗
2

NCT01160861 ↗

NCT01196039 ↗

Known as MEP-1972A ChEMBL registry synonym — accepted as the source's own label CHEMBL2109456 ↗
Known as RG-7449 ChEMBL registry synonym — accepted as the source's own label CHEMBL2109456 ↗
Action Inhibit “Ig epsilon chain C region inhibitor” CHEMBL2109456 ↗
Modality Monoclonal antibody — CHEMBL2109456 ↗
Route Subcutaneous “Two administrations by subcutaneous injection” NCT01987947 ↗
Target IGHE “Ig epsilon chain C region inhibitor” CHEMBL2109456 ↗