Drugs / OMIPALISIB
last change Jul 2016 re-read 2 minutes ago

OMIPALISIB

also known as GSK2126458

Small molecule targets MTOR via inhibition

Developed for
cancer · idiopathic pulmonary fibrosis
Investigated by
GlaxoSmithKline

Trials 3 · a red edge is where a trial was stopped

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01725139 Mar 2013 → Jul 2016 idiopathic pulmonary fibrosis GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT01248858 Dec 2010 → Jan 2014 cancer GlaxoSmithKline Terminated No outcome recorded
Phase 1 NCT00972686 Aug 2009 → Dec 2012 cancer GlaxoSmithKline Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as OMIPALISIB ChEMBL registry synonym — accepted as the source's own label CHEMBL1236962
Known as GSK2126458 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01725139
2

NCT01248858

NCT00972686

Action Inhibit “Phosphoinositide 3-Kinase Inhibitor GSK2126458” NCT00972686
Modality Small molecule CHEMBL1236962
Route Oral “Subjects with solid tumors or lymphoma will initially receive oral GSK2126458 daily for 28 consecutive days in each 28 day cycle” NCT00972686
Target MTOR “GSK2126458 is a novel, potent, PI3K/mammalian target of rapamycin (mTOR) inhibitor” PMID 27103349 Apr 2016