Drugs / Nepadutant
last change Mar 2014 re-read 3 minutes ago

Nepadutant

Protein / enzyme biologic targets TACR2 via inhibition

Developed for
infantile diarrhea
Investigated by
Menarini Group

Trials 4

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00655083 Mar 2008 → May 2009 — Menarini Group Completed No outcome recorded
Phase 23 trials
Phase 2 NCT01532518 Aug 2011 → Jul 2012 — Menarini Group Completed No outcome recorded
Phase 2 NCT01309009 Feb 2011 → Nov 2012 infantile diarrhea Menarini Group Withdrawn No outcome recorded
Phase 2 NCT01258153 Nov 2010 → Dec 2013 — Menarini Group Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Nepadutant ClinicalTrials.gov intervention name — accepted as the source's own label NCT01258153 ↗
3

NCT01309009 ↗

NCT01532518 ↗

NCT00655083 ↗

Action Inhibit “Neurokinin 2 receptor antagonist” CHEMBL1908318 ↗
Modality Protein / enzyme biologic — CHEMBL1908318 ↗
Route Oral “0.1 mg/Kg as one single oral dose divided in three age strata (from 6 to 24 weeks old)” NCT00655083 ↗
Target TACR2 “Neurokinin 2 receptor antagonist” CHEMBL1908318 ↗