Drugs / Procaterol
Procaterol
also known as
Procaterol Hydrochloride · CI-888 · Meptin · Meptin Air · Meptin Swinghaler · Pro-air · Procaterol HCL
Other / unclassified targets ADRB2 via activation
Trials 9
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT02165033 | Nov 2012 → Jan 2013 | asthma | Intech Biopharm Ltd. | Completed | No outcome recorded |
| Phase 1 | NCT02165046 | Feb → Apr 2012 | asthma, chronic obstructive pulmonary disease | Intech Biopharm Ltd. | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT02162784 | Feb 2013 → Aug 2014 | asthma | Intech Biopharm Ltd. | Completed | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT01076322 | Mar 2009 → Jun 2010 | asthma | Taiwan Otsuka Pharm. Co., Ltd | Completed | No outcome recorded |
| Phase 3 | NCT00990847 | Jun 2007 → Apr 2008 | acute asthma | PT Otsuka Indonesia | Completed | No outcome recorded |
| Phase 43 trials | ||||||
| Phase 4 | NCT01170429 | Jul 2010 → Feb 2011 | cough variant asthma | Shanghai Jiao Tong University School of Medicine | Unknown | No outcome recorded |
| Phase 4 | NCT01091337 | May 2006 → Sep 2009 | asthma | Otsuka Pharmaceutical Co., Ltd. | Completed | No outcome recorded |
| Phase 4 | NCT00394485 | May 2006 → Apr 2008 | chronic obstructive pulmonary disease | Otsuka Pharmaceutical Co., Ltd. | Terminated | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT02349919 | Mar 2015 → Dec 2017 | cough variant asthma | Mahidol University | Unknown | No outcome recorded |
| Comparator or background therapy2 trials | ||||||
| Phase 4 | NCT06346691 Comparator | Mar → Oct 2024 | chronic obstructive pulmonary disease | Thammasat University | Completed | No outcome recorded |
| — | NCT02790047 Background | Oct 2016 → Jan 2018 | chronic obstructive pulmonary disease | Khon Kaen University | Unknown | No outcome recorded |
News releases announcing trial results or a regulatory action · 2
| Date | Issuer | Release |
|---|---|---|
| 2014-02-17 | Otsuka Pharmaceutical Development & Commercialization, Inc. | Regulatory Meptin Swinghaler, Easy-to-inhale Bronchodilator for COPD and Asthma Patients, Approved in Japan otsuka.co.jp ↗
Tokyo, Japan, February 17, 2013 - Otsuka Pharmaceutical Co., Ltd. received regulatory approval on February 14 in Japan for Meptin Swinghaler (procaterol hydrochloride hydrate) 10μg, 100 puffs. |
| 2013-01-11 | Otsuka Pharmaceutical Development & Commercialization, Inc. | Regulatory Otsuka Pharmaceutical Files for Application of New Dry Powder Inhaler Product from the Meptin Brand otsuka.co.jp ↗
Otsuka Pharmaceutical Co., Ltd. today announced that the company submitted a manufacturing and marketing approval application for procaterol hydrochloride hydrate in dry powder inhaler form, in December 2012. |
All press releases naming this drug 3 releases
| Date | Issuer | Release |
|---|---|---|
| 2014-06-20 | Otsuka Pharmaceutical Development & Commercialization, Inc. | Meptin, a Fast-acting Bronchodilator to Treat Asthma and COPD, Will Become Available in Japan on July 2 in a New Form as Meptin Swinghaler 10μg 100Puffs®®® otsuka.co.jp ↗ |
| 2014-02-17 | Otsuka Pharmaceutical Development & Commercialization, Inc. | Meptin Swinghaler, Easy-to-inhale Bronchodilator for COPD and Asthma Patients, Approved in Japan otsuka.co.jp ↗ |
| 2013-01-11 | Otsuka Pharmaceutical Development & Commercialization, Inc. | Otsuka Pharmaceutical Files for Application of New Dry Powder Inhaler Product from the Meptin Brand otsuka.co.jp ↗ |
Evidence & citations 12 cited values
Every value below carries the sentence it was read from. 12 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Procaterol | “Meptin® Swinghaler® * Ingredient: Procaterol HCL” NCT01076322 ↗ |
| Known as | CI-888 | ChEMBL registry synonym — accepted as the source's own label CHEMBL160519 ↗ |
| Known as | Meptin | ChEMBL registry synonym — accepted as the source's own label CHEMBL160519 ↗ |
| Known as | Meptin Air | “Reference drug 2 : Meptin Air 10ug (Procaterol Hydrochloride) Strength: (Procaterol Hydrochloride 10ug/puff) Mode of administration: Orally inhaled administration, single dose (4 puffs)” NCT02165046 ↗ |
| Known as | Meptin Swinghaler | “Meptin® Swinghaler® * Ingredient: Procaterol HCL” NCT01076322 ↗ |
| Known as | Pro-air | ChEMBL registry synonym — accepted as the source's own label CHEMBL160519 ↗ |
| Known as | Procaterol HCL | “Meptin® Swinghaler® * Ingredient: Procaterol HCL” NCT01076322 ↗ |
| Known as | Procaterol Hydrochloride | “Reference drug 2 : Meptin Air 10ug (Procaterol Hydrochloride) Strength: (Procaterol Hydrochloride 10ug/puff) Mode of administration: Orally inhaled administration, single dose (4 puffs)” NCT02165046 ↗1“Meptin (Procaterol hydrochloride) Tablets” NCT01170429 ↗ |
| Action | Activate | “Beta-2 adrenergic receptor agonist” CHEMBL160519 ↗1“a beta agonist (procaterol)” NCT00394485 ↗ |
| Modality | Other / unclassified | “Procaterol is a direct acting sympathomimetic with predominantly Beta-adrenoceptor stimulant activity selective to Beta-2 receptors (a Beta-2 agonist).” NCT02165033 ↗ |
| Route | Other | “Procaterol inhalation solution 50 micro g per 0.5 mL diluted in 2mL of NaCl 0.9%” NCT00990847 ↗ |
| Target | ADRB2 | “Beta-2 adrenergic receptor agonist” CHEMBL160519 ↗ |