Drugs / FPV-Brachyury
last change Oct 2024 re-read 2 minutes ago

FPV-Brachyury

Vaccine

Developed for
castration-resistant prostate carcinoma · chordoma
Investigated by
Bavarian Nordic · National Cancer Institute (NCI)

Trials 4 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03349983 Jan 2018 → Jun 2020 Bavarian Nordic Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT03493945 May 2018 → Oct 2024 castration-resistant prostate carcinoma National Cancer Institute (NCI) Completed No outcome recorded
Phase 22 trials
Phase 2 NCT05445882 Apr 2024 castration-resistant prostate carcinoma National Cancer Institute (NCI) Withdrawn No outcome recorded
Phase 2 NCT03595228 Oct 2018 → Dec 2021 chordoma Bavarian Nordic Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as FPV-Brachyury FPV-Brachyury injection will be given on day 28, followed by radiation on days 42 through approximately day 70.” NCT03595228
3

“BN-Brachyury collectively refers to the priming doses (MVA-BN-Brachyury) and the boost doses (FPV-Brachyury).” NCT05445882

NCT03493945

NCT03349983

Modality Vaccine “MVA-BN-Brachyury priming and FPV-Brachyury boost vaccines” NCT03349983
Route Subcutaneous “FPV-brachyury s.c., 1 × 109 IU” PMID 31876334 Dec 2019