Drugs / 18F-FDG
last change 11 days ago re-read 9 days ago

18F-FDG

Diagnostic / imaging agent

Investigated by
National Cancer Institute (NCI) · Peking Union Medical College Hospital · First Affiliated Hospital of Fujian Medical University · Peking University Cancer Hospital & Institute · Rigshospitalet, Denmark · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
+49 more · Affiliated Hospital of Jiangnan University · Andrei Iagaru · GE Healthcare · Stanford University · University of California, San Francisco · University of Washington · Washington University School of Medicine · Affiliated Hospital of North Sichuan Medical College · Akiva Mintz · Andalusian Public Foundation for Health Research in Seville · Assistance Publique - Hôpitaux de Paris · Avid Radiopharmaceuticals · Boston University · Canary Foundation · Centre Hospitalier Universitaire de la Réunion · Chang Gung Memorial Hospital · Emory University · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · First Hospital of China Medical University · H. Lee Moffitt Cancer Center and Research Institute · Hua Zhu · M.D. Anderson Cancer Center · Massachusetts General Hospital · Mayo Clinic · NRG Oncology · National Heart, Lung, and Blood Institute (NHLBI) · National Institute for Biomedical Imaging and Bioengineering (NIBIB) · National Institute on Alcohol Abuse and Alcoholism (NIAAA) · National Institutes of Health (NIH) · National Science and Technology Council, Taiwan · Ohio State University Comprehensive Cancer Center · Peking University First Hospital · Randy Yeh · RefleXion Medical · Rutgers, The State University of New Jersey · Sinotau Pharmaceutical Group · Society of Abdominal Radiology · The Society of Nuclear Medicine and Molecular Imaging · United States Department of Defense · University Health Network, Toronto · University Hospital, Bordeaux · University Medical Center Groningen · University of Alabama at Birmingham · University of California, Davis · University of Michigan · University of Pennsylvania · West Virginia University · Yantai LNC Biotechnology Singapore PTE. LTD. · Zhejiang University

Regulatory milestones approvals, filings & regulatory actions · 2 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansion US (FDA) FLUDEOXYGLUCOSE F18 — 2000-06-02 fda.gov ↗
Approved US (FDA) FLUDEOXYGLUCOSE F18 — 1994-08-19 fda.gov ↗

Trials 68 · started per year

today
US approved 1994
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 015 trials
Phase 0 NCT07604207 Jul 2026 → Jul 2031 expected cardiovascular disorder Massachusetts General Hospital Not yet recruiting No outcome recorded
Phase 0 NCT07023861 Jul 2025 → Jul 2026 overdue breast cancer, gastric cancer, urothelial carcinoma Affiliated Hospital of Jiangnan University Enrolling by invitation No outcome recorded
Phase 0 NCT07023848 Jul 2025 → Jul 2026 overdue breast cancer, gastric cancer, urothelial carcinoma Affiliated Hospital of Jiangnan University Enrolling by invitation No outcome recorded
Phase 0 NCT07301801 Jun 2025 → Sep 2026 overdue cancer Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Recruiting No outcome recorded
Phase 0 NCT06455761 Apr 2024 → Apr 2025 neoplasm First Affiliated Hospital of Fujian Medical University Unknown No outcome recorded
Phase 0 NCT06455735 Mar 2024 → Dec 2025 neoplasm First Affiliated Hospital of Fujian Medical University Unknown No outcome recorded
Phase 0 NCT06014515 Feb 2024 → Aug 2028 expected cardiovascular disorder University of California, Davis Recruiting No outcome recorded
Phase 0 NCT06126705 Jul 2023 → May 2024 — Affiliated Hospital of North Sichuan Medical College Unknown No outcome recorded
Phase 0 NCT05543954 Sep 2022 → Dec 2025 overdue lung neoplasm Peking Union Medical College Hospital Recruiting No outcome recorded
Phase 0 NCT05549024 Aug 2022 → Dec 2025 overdue brain neoplasm, breast cancer, prostate cancer Peking Union Medical College Hospital Recruiting No outcome recorded
Phase 19 trials
Phase 1 NCT07838649 Nov 2026 → Dec 2029 expected Hodgkins lymphoma, breast cancer, non-Hodgkin lymphoma Washington University School of Medicine Not yet recruiting No outcome recorded
Phase 1 NCT06203119 Mar 2024 → Dec 2025 cancer Peking University Cancer Hospital & Institute Completed No outcome recorded
Phase 1 NCT05121779 Nov 2021 → Dec 2025 overdue pulmonary fibrosis Peking Union Medical College Hospital Recruiting No outcome recorded
Phase 1 NCT03493789 Apr 2018 → Mar 2019 carcinoma, lung cancer Emory University Completed No outcome recorded
Phase 1 NCT03590769 Jun 2017 → Sep 2019 calcinosis, intermittent vascular claudication, peripheral arterial disease University of California, San Francisco Completed No outcome recorded
Phase 1 NCT02891616 Oct 2016 → Dec 2017 melanoma Washington University School of Medicine Terminated No outcome recorded Stop: Enrollment
Phase 1 NCT02429804 Apr 2015 → May 2017 hormone-resistant prostate carcinoma, metastatic carcinoma in the bone, metastatic prostate carcinoma Stanford University Terminated No outcome recorded Stop: Enrollment
Phase 1 NCT03195270 Nov 2014 → Jan 2022 chronic pain syndrome Stanford University Completed No outcome recorded
Phase 1 NCT03404414 Feb 2013 → Nov 2018 pituitary gland adenoma Peking Union Medical College Hospital Unknown No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT04273555 Mar 2026 → Jun 2028 HER2 positive breast carcinoma University of Alabama at Birmingham Withdrawn No outcome recorded Stop: Enrollment
Phase 1/2 NCT05506566 May 2022 → May 2025 neoplasm First Affiliated Hospital of Fujian Medical University Unknown No outcome recorded
Phase 1/2 NCT05515783 May 2022 → May 2024 neoplasm First Affiliated Hospital of Fujian Medical University Unknown No outcome recorded
Phase 219 trials · 1 missed
Phase 2 NCT07285993 Jun 2026 → Dec 2027 expected invasive lobular breast carcinoma Randy Yeh Not yet recruiting No outcome recorded
Phase 2 NCT07443696 Dec 2025 → Aug 2026 overdue cardiomyopathy, heart failure Sinotau Pharmaceutical Group Recruiting No outcome recorded
Phase 2 NCT06503146 Sep 2025 → Jun 2028 expected cholangiocarcinoma, gastric cancer, hepatocellular carcinoma, mesothelioma +6 National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 2 NCT06956391 May 2025 → Jun 2030 expected cancer Akiva Mintz Recruiting No outcome recorded
Phase 2 NCT05709171 Jan 2023 → Jan 2025 digestive system neuroendocrine neoplasm, neuroendocrine carcinoma Rigshospitalet, Denmark Unknown No outcome recorded
Phase 2 NCT05396118 May 2022 → Aug 2024 breast cancer, lymphoma, neuroendocrine carcinoma, sarcoma Rigshospitalet, Denmark Unknown No outcome recorded
Phase 2 NCT04692103 Jul → Oct 2021 overdue estrogen-receptor positive breast cancer University of Washington Active not recruiting No outcome recorded
Phase 2 NCT03824535 Feb 2019 → Jul 2021 pulmonary coin lesion Andrei Iagaru Completed No outcome recorded
Phase 2 NCT03602911 Feb 2019 → Apr 2021 head and neck squamous cell carcinoma West Virginia University Completed No outcome recorded
Phase 2 NCT03173924 Jun 2017 → Feb 2028 expected metastatic prostate carcinoma National Cancer Institute (NCI) Active not recruiting No outcome recorded
Phase 33 trials
Phase 3 NCT06416852 Aug 2024 → Aug 2026 overdue non-small cell lung carcinoma Yantai LNC Biotechnology Singapore PTE. LTD. Not yet recruiting No outcome recorded
Phase 3 NCT04831619 Dec 2023 → Apr 2025 endometriosis Centre Hospitalier Universitaire de la Réunion Completed No outcome recorded
Phase 3 NCT03891914 Nov 2019 → Jan 2023 plasma cell myeloma University Hospital, Bordeaux Completed No outcome recorded
Phase 43 trials
Phase 4 NCT05463913 Jul 2022 → Jun 2025 overdue lung cancer University Medical Center Groningen Recruiting No outcome recorded
Phase 4 NCT03937583 Oct 2019 → Dec 2023 lung disorder, pulmonary embolism, venous thromboembolism Andalusian Public Foundation for Health Research in Seville Unknown No outcome recorded
Phase 4 NCT03549598 Jul 2018 → Oct 2019 cardiac sarcoidosis Mayo Clinic Completed No outcome recorded
Phase not applicable16 trials
— NCT07589101 Jun 2026 → Jun 2027 expected breast cancer, lung cancer Peking University Cancer Hospital & Institute Not yet recruiting No outcome recorded
— NCT07553741 Apr → Dec 2025 breast cancer Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Completed No outcome recorded
— NCT06630845 Feb 2025 → Oct 2027 expected metastatic malignant neoplasm University of California, San Francisco Recruiting No outcome recorded
— NCT07366710 Nov 2024 → Oct 2027 expected NAFLD1, glucose metabolism disease Rigshospitalet, Denmark Active not recruiting No outcome recorded
— NCT06429891 Aug 2024 → Dec 2026 expected neoplasm Hua Zhu Recruiting No outcome recorded
— NCT05999227 Jun → Dec 2023 rectal cancer Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Unknown No outcome recorded
— NCT05840094 May 2023 → May 2025 lung neoplasm Peking University First Hospital Unknown No outcome recorded
— NCT05803746 Jul 2022 → Jul 2024 colorectal cancer, lung cancer Peking University Cancer Hospital & Institute Unknown No outcome recorded
— NCT05436093 Jun 2022 → Dec 2026 expected neoplasm Peking University Cancer Hospital & Institute Recruiting No outcome recorded
— NCT05432947 Apr → Sep 2022 clear cell renal carcinoma Peking Union Medical College Hospital Completed No outcome recorded
Comparator or background therapy18 trials
Phase 0 NCT04016818 Background Jun 2026 → Dec 2027 breast cancer Stanford University Withdrawn No outcome recorded Stop: Business
Phase 0 NCT06717113 Comparator Apr → Dec 2025 overdue plasma cell myeloma Peking University First Hospital Recruiting No outcome recorded
Phase 0 NCT06740240 Comparator Mar 2024 → Jun 2026 overdue neoplasm First Affiliated Hospital of Fujian Medical University Recruiting No outcome recorded
Phase 0 NCT02405078 Background Oct 2015 → Oct 2022 diffuse large B-cell lymphoma M.D. Anderson Cancer Center Completed No outcome recorded
Phase 1 NCT01494012 Background Apr → Sep 2012 malignant epithelial tumor of ovary, malignant germ cell tumor of ovary, peritoneum cancer Stanford University Terminated No outcome recorded Stop: Enrollment

Evidence & citations 15 cited values

Every value below carries the sentence it was read from. 88 sources stand behind the page.

FieldValueCited text
Known as 18F FDG “After confirmation of a blood glucose level ≤200 mg/dl, technologists will establish the intravenous access and the subject will receive approximately 10 mCi of 18F-FDG...” NCT03123289 ↗
63

“Participants with various types of cancer will have PET imaging 50-100 minutes after injection of 68Ga-FAP-CHX and another agent (68Ga-FAPI-04 or 18F-FDG).” NCT05506566 ↗

“PET Myocardial Fatty-acid Metabolic Imaging With XTR003 Injection and 18F-FDG to Assess Myocardial Viability in Ischemic Cardiomyopathy” NCT07443696 ↗

“18F-FDG, the dose will be 3.7 (MBq / kg) given intravenously at a single time prior to imaging.” NCT05515783 ↗

“Initial intravenous injection of 18F-FDG to each subject” NCT05885854 ↗

“The 18F-FDG injection procedure will be injected” NCT01237054 ↗

“18 F FDG followed by PET/CT imaging” NCT01394679 ↗

“Drug: 18F FDG PET/CT scan” NCT03123289 ↗

NCT06455761 ↗

NCT05396118 ↗

NCT06416852 ↗

Show 53 more sources

Known as 18-FDG ClinicalTrials.gov intervention name — accepted as the source's own label NCT00001849 ↗
3

NCT03549598 ↗

NCT04831619 ↗

NCT01471418 ↗

Known as 18-fluorodeoxyglucose “18-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) for treatment response evaluation” PMID 32909953 ↗ Sep 2020
1

“18-fluorodeoxyglucose (18-FDG), a radioisotope used with positron emission tomography (PET)” NCT01471418 ↗

Known as 18F-2-fluoro-2-deoxy-D-glucose “PET scanner with injection of 18 FDG (18F-2-fluoro-2-deoxy-D-glucose) (radiolabel)” NCT04831619 ↗
Known as 18F-fluorodeoxyglucose “OBJECTIVE: The goal of this study is to demonstrate the feasibility of simultaneous [18F]-fluorodeoxyglucose (FDG) positron emission tomography (PET) and magnetic resonance...” PMID 34718774 ↗ Feb 2022
10

“Intravenous bolus administration of 18F-fluorodeoxyglucose (18F-FDG) for total-body PET/CT to measure systemic biodistribution and whole-body glucose metabolism.” NCT07366710 ↗

“subjects are injected with 18F-Fluorodeoxyglucose (18F-FDG), a radioactively labeled glucose molecule which is consumed by macrophages.” NCT03590769 ↗

“18F-Fluorodeoxyglucose (FDG)-PET session to assess the association between FC and glucose metabolism in the human brain.” NCT02193425 ↗

“18F-fluorodeoxyglucose or FDG (to measure whether heart muscle cells are alive)” NCT02003456 ↗

“This scan is done with a radiotracer called 18F-fluorodeoxyglucose (FDG).” NCT04417998 ↗

“18F-Fluorodeoxyglucose (FDG) injection” NCT00887718 ↗

NCT02003456 ↗

NCT06125028 ↗

NCT02074202 ↗

NCT05390021 ↗

Known as 2-\[18F\]-fluoro-2-deoxy-D-glucose “2-\[18F\]-fluoro-2-deoxy-D-glucose, called \[18F\]FDG, is a radioactive sugar that is widely used for cancer imaging” NCT02074202 ↗
Known as 2-deoxy-2-[18F]fluoro-D-glucose ClinicalTrials.gov intervention name — accepted as the source's own label NCT03295695 ↗
Known as [18F]-Fluorodeoxyglucose ([18F]-FDG) “[18F]-Fluorodeoxyglucose ([18F]-FDG)” NCT02599194 ↗
Known as FDG “OBJECTIVE: The goal of this study is to demonstrate the feasibility of simultaneous [18F]-fluorodeoxyglucose (FDG) positron emission tomography (PET) and magnetic resonance...” PMID 34718774 ↗ Feb 2022
6

“subjects are injected with 18F-Fluorodeoxyglucose (18F-FDG), a radioactively labeled glucose molecule which is consumed by macrophages.” NCT03590769 ↗

“18F-fluorodeoxyglucose or FDG (to measure whether heart muscle cells are alive)” NCT02003456 ↗

“[18F]-Fluorodeoxyglucose (FDG) PET/ MRI” NCT04273555 ↗

“18F-Fluorodeoxyglucose (FDG) injection” NCT00887718 ↗

“2-deoxy-2-[18F]fluoro-D-glucose (FDG)” NCT03295695 ↗

NCT01394679 ↗

Known as Fludeoxyglucose 18F ClinicalTrials.gov intervention name — accepted as the source's own label NCT03937583 ↗
Known as Fludeoxyglucose F-18 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02149173 ↗
9

NCT03493789 ↗

NCT04692103 ↗

NCT01507428 ↗

NCT03824535 ↗

NCT02891616 ↗

NCT02405078 ↗

NCT01494012 ↗

NCT02429804 ↗

NCT04219969 ↗

Known as fluorodeoxyglucose “with the injection of a radiopharmaceutical drug, the 18F-FDG (or fluorodeoxyglucose) for the detection of bone lesions” NCT03891914 ↗
1

“[18F]-Fluorodeoxyglucose (FDG) PET/ MRI” NCT04273555 ↗

Known as Fluorodeoxyglucose F18 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06630845 ↗
Modality Diagnostic / imaging agent “FDG PET scan of body” NCT00001849 ↗
Route Intravenous “will receive a preoperative IV injection into a peripheral vein of 15 mCi of 18FFDG” NCT00816335 ↗