Drugs / biricodar
last change Feb 2001 re-read 3 minutes ago

biricodar

also known as VX-71O-3

Small molecule targets ABCB1, ABCC1 via inhibition

Developed for
small cell lung carcinoma
Investigated by
Vertex Pharmaceuticals Incorporated

Trials 1

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00003847 Dec 1998 → Feb 2001 small cell lung carcinoma Vertex Pharmaceuticals Incorporated Terminated Missed primary

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as biricodar ClinicalTrials.gov intervention name — accepted as the source's own label NCT00003847 ↗
Known as VX-71O-3 ChEMBL registry synonym — accepted as the source's own label CHEMBL350775 ↗
Action Inhibit “Multidrug resistance-associated protein 1 inhibitor” CHEMBL350775 ↗
1

“P-glycoprotein 1 inhibitor” CHEMBL350775 ↗

Modality Small molecule — CHEMBL350775 ↗
Target ABCB1 “P-glycoprotein 1 inhibitor” CHEMBL350775 ↗
Target ABCC1 “Multidrug resistance-associated protein 1 inhibitor” CHEMBL350775 ↗