Drugs / IONIS GHR-LRx
last change Jul 2022 re-read 2 minutes ago

IONIS GHR-LRx

also known as ISIS 766720

Antisense oligonucleotide targets GHR via inhibition

Developed for
acromegaly
Investigated by
Ionis Pharmaceuticals, Inc.

Trials 2 · a red edge is where a trial was stopped

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT03967249 Jul 2019 → Mar 2022 acromegaly Ionis Pharmaceuticals, Inc. Completed No outcome recorded
Phase 2 NCT03548415 Sep 2018 → Feb 2021 acromegaly Ionis Pharmaceuticals, Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as IONIS GHR-LRx “A Double-Blind, Placebo-Controlled, Phase 2 Study to Assess the Safety, Tolerability, and Efficacy of ISIS 766720 (IONIS-GHR-LRx, an Antisense Inhibitor of the Growth Hormone Receptor)” NCT03548415
2

NCT03548415

NCT03967249

Known as ISIS 766720 “A Double-Blind, Placebo-Controlled, Phase 2 Study to Assess the Safety, Tolerability, and Efficacy of ISIS 766720 (IONIS-GHR-LRx, an Antisense Inhibitor of the Growth Hormone Receptor)” NCT03548415
Action Inhibit “an Antisense Inhibitor of the Growth Hormone Receptor” NCT03548415
Modality Antisense oligonucleotide “an Antisense Inhibitor” NCT03548415
Route Subcutaneous “IONIS GHR-LRx administered subcutaneously.” NCT03548415
Target GHR “an Antisense Inhibitor of the Growth Hormone Receptor” NCT03548415