Drugs / APG777
last change 3 days ago re-read 2 minutes ago

APG777

Monoclonal antibody targets IL13 via inhibition

Developed for
atopic eczema · asthma
Investigated by
Apogee Therapeutics, Inc.

Trials 4 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT07027527 Jun 2025 → Dec 2026 expected atopic eczema Apogee Therapeutics, Inc. Active not recruiting No outcome recorded
Phase 1 NCT06920901 Mar 2025 → Sep 2026 expected asthma Apogee Therapeutics, Inc. Active not recruiting No outcome recorded
Phase 22 trials
Phase 2 NCT07003425 May 2025 → Dec 2029 expected atopic eczema Apogee Therapeutics, Inc. Recruiting No outcome recorded
Phase 2 NCT06395948 Apr 2024 → Nov 2026 expected atopic eczema Apogee Therapeutics, Inc. Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as APG777 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06395948
3

NCT07003425

NCT07027527

NCT06920901

Action Inhibit “Preclinical Safety of APG777, A Novel Extended Half-Life Anti-Interleukin-13 Monoclonal Antibody” PMID 40739793 Jul 2025
Modality Monoclonal antibody “APG777 is a humanized IgG1 monoclonal antibodyPMID 40739793 Jul 2025
Route Subcutaneous “APG777 subcutaneous injection” NCT06395948
Target IL13 “APG777 has high affinity to IL-13” PMID 40739793 Jul 2025