Drugs / PETESICATIB
last change Jul 2017 re-read 3 minutes ago

PETESICATIB

also known as RG7625 · RO5459072

Small molecule targets CTSS via inhibition

Developed for
celiac disease · Sjogren syndrome
Investigated by
Hoffmann-La Roche

Trials 4

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials · 1 missed
Phase 1 NCT02679014 Mar → Aug 2016 celiac disease Hoffmann-La Roche Completed Missed primary
Phase 1 NCT02521610 Aug → Nov 2015 — Hoffmann-La Roche Completed No outcome recorded
Phase 1 NCT02295332 Dec 2014 → Apr 2015 — Hoffmann-La Roche Completed No outcome recorded
Phase 21 trial · 1 missed
Phase 2 NCT02701985 Jul 2016 → Jul 2017 Sjogren syndrome Hoffmann-La Roche Completed Missed primary

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as PETESICATIB ChEMBL registry synonym — accepted as the source's own label CHEMBL4297638 ↗
Known as RG7625 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02521610 ↗
1

NCT02295332 ↗

Known as RO5459072 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02701985 ↗
1

NCT02679014 ↗

Action Inhibit “RO5459072, a cathepsin S inhibitor” NCT02679014 ↗
Modality Small molecule — CHEMBL4297638 ↗
Route Oral “Participants will receive RG7625 as oral capsules once or twice daily for 8 days.” NCT02521610 ↗
Target CTSS “RO5459072, a cathepsin S inhibitor” NCT02679014 ↗