Drugs / TQB3616

Trials 15 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT06662773 Nov 2024 → Mar 2025 overdue Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Not yet recruiting No outcome recorded
Phase 1 NCT06149611 Jan → Jun 2024 breast cancer Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Unknown No outcome recorded
Phase 1 NCT05344729 Jul → Aug 2021 breast carcinoma Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Completed No outcome recorded
Phase 1 NCT03850873 May 2019 → Sep 2021 breast cancer Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Completed No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT06851442 May → Nov 2025 breast cancer Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Terminated No outcome recorded
Phase 1/2 NCT06202261 Apr 2023 → Dec 2026 expected breast carcinoma Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT05139082 Nov 2021 → Oct 2023 digestive system neoplasm Peking University Unknown No outcome recorded
Phase 25 trials
Phase 2 NCT06702618 Feb 2025 → Jun 2026 overdue breast cancer Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Active not recruiting No outcome recorded
Phase 2 NCT05496569 Aug 2022 → Jun 2024 dedifferentiated liposarcoma Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Terminated No outcome recorded
Phase 2 NCT05156450 Jan 2022 → Oct 2023 castration-resistant prostate carcinoma West China Hospital Unknown No outcome recorded
Phase 2 NCT04924192 Aug 2021 → Sep 2022 lung carcinoma Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Terminated No outcome recorded
Phase 2 NCT04796623 Feb 2021 → May 2024 hormone receptor-positive breast cancer Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Completed No outcome recorded
Phase 33 trials
Phase 3 NCT05780567 Mar 2023 → Dec 2026 expected breast cancer Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Active not recruiting No outcome recorded
Phase 3 NCT05365178 Jul 2022 → Jul 2025 overdue hormone receptor-positive breast cancer Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Active not recruiting No outcome recorded
Phase 3 NCT05375461 Mar 2022 → Jan 2024 hormone receptor-positive breast cancer Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 16 sources stand behind the page.

FieldValueCited text
Known as TQB3616 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05139082
14

NCT06662773

NCT05365178

NCT05780567

NCT04796623

NCT05375461

NCT05496569

NCT06702618

NCT06149611

NCT05156450

NCT03850873

NCT04924192

NCT06202261

NCT06851442

NCT05344729

Known as culmerciclib “Novel CDK2/4/6 inhibitor culmerciclib (TQB3616) plus fulvestrant in previously treated, HR-positive, HER2-negative advanced breast cancer: a randomized, double-blind, phase 3 trial.” PMID 41413016 Dec 2025
Action Inhibit “TQB3616 may work in cancer by stopping cancer cells from multiplying.” NCT03850873
Modality Small molecule “TQB3616 capsule is a small molecule oral drug” NCT05344729
Route Oral “TQB3616 is taken by mouth daily.” NCT03850873
Target CDK4 “A CDK4/6 kinase inhibitor” NCT04924192