drugset
Drugs / SECRETIN SYNTHETIC HUMAN
last change Jun 2023 re-read 3 minutes ago

SECRETIN SYNTHETIC HUMAN

also known as Synthetic Human Secretin · ChiRhoStim · Human Secretin · Secretin (human) · Secretin (human), acetate (salt) · Secretin acetate human · Secretin human acetate · Secretin human pentaacetate · +2 more

Peptide targets SCTR via activation

Developed for
chronic pancreatitis
Investigated by
ChiRhoClin, Inc. · Dartmouth-Hitchcock Medical Center · Mayo Clinic

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) CHIRHOSTIM — 2004-04-09 fda.gov ↗

Trials 2

today
US approved 2004
NCT01265875 · Ph 1/2 NCT00587132 · Ph 1/2
200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/22 trials · 1 missed
Phase 1/2 NCT01265875 Dec 2010 → Dec 2011 chronic pancreatitis ChiRhoClin, Inc. Completed Missed primary
Phase 1/2 NCT00587132 Nov 2006 → Feb 2012 pancreatic adenocarcinoma Mayo Clinic Terminated No outcome recorded Stop: Business
Comparator or background therapy5 trials
Phase 3 NCT04231279 Background Jan 2022 → Jun 2023 irritable bowel syndrome Orlando Health, Inc. Terminated No outcome recorded
Phase 3 NCT01087801 Comparator Oct 2007 → Nov 2009 pancreas disorder ChiRhoClin, Inc. Completed No outcome recorded
— NCT01094600 Background Jun 2012 malignant pancreatic neoplasm Columbia University Withdrawn No outcome recorded
— NCT01094535 Background Sep 2007 → Sep 2012 malignant pancreatic neoplasm Columbia University Withdrawn No outcome recorded Stop: Enrollment
— NCT01094561 Background Jul 2006 → Feb 2015 malignant pancreatic neoplasm Elizabeth Hecht Completed No outcome recorded

Evidence & citations 15 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as SECRETIN SYNTHETIC HUMAN ChEMBL registry synonym — accepted as the source's own label CHEMBL1201488 ↗
Known as ChiRhoStim ClinicalTrials.gov intervention name — accepted as the source's own label NCT01087801 ↗
Known as Human Secretin ClinicalTrials.gov intervention name — accepted as the source's own label NCT01265875 ↗
Known as Secretin (human) ChEMBL registry synonym — accepted as the source's own label CHEMBL1201488 ↗
Known as Secretin (human), acetate (salt) ChEMBL registry synonym — accepted as the source's own label CHEMBL1201488 ↗
Known as Secretin acetate human ChEMBL registry synonym — accepted as the source's own label CHEMBL1201488 ↗
Known as Secretin human acetate ChEMBL registry synonym — accepted as the source's own label CHEMBL1201488 ↗
Known as Secretin human pentaacetate ChEMBL registry synonym — accepted as the source's own label CHEMBL1201488 ↗
Known as Secretina humana ChEMBL registry synonym — accepted as the source's own label CHEMBL1201488 ↗
Known as Secretine humaine ChEMBL registry synonym — accepted as the source's own label CHEMBL1201488 ↗
Known as Synthetic Human Secretin “Synthetic Human Secretin (ChiRhoStim®) Administered Intravenously to Stimulate Exocrine Pancreas Fluid Secretion” NCT01087801 ↗
5

NCT01094600 ↗

NCT01094535 ↗

NCT01094561 ↗

NCT04231279 ↗

NCT00587132 ↗
Action Activate “Secretin receptor agonist” CHEMBL1201488 ↗
Modality Peptide “Secretin is a gastrointestinal peptide hormone” NCT04231279 ↗
Route Intravenous “Secretin will be given intravenously (0.2 mcg/kg IV slowly over one minute).” NCT00587132 ↗
Target SCTR “Secretin receptor agonist” CHEMBL1201488 ↗