Drugs / DT388IL3
last change Jul 2017 re-read 3 minutes ago

DT388IL3

also known as SL-401

Protein / enzyme biologic

Developed for
CD4+/CD56+ hematodermic neoplasm · leukemia · myelodysplastic syndrome
Investigated by
University of Texas Southwestern Medical Center

Trials 1

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT00397579 May 2013 → Jul 2017 CD4+/CD56+ hematodermic neoplasm, leukemia, myelodysplastic syndrome University of Texas Southwestern Medical Center Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as DT388IL3 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00397579 ↗
Known as SL-401 “Because BPDCN blasts overexpress the interleukin-3 receptor (IL3R), the activity of SL-401, diptheria toxin (DT)388IL3 composed of the catalytic and translocation domains of DT...” PMID 24859366 ↗ May 2014
Modality Protein / enzyme biologic “DT388IL3 fusion protein” NCT00397579 ↗
Route Intravenous “Intravenously via a 3 cc plastic syringe as a 15 minute bolus infusion daily for five days” NCT00397579 ↗