Drugs / Diosmin

Trials 19 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT04452799 Jul → Oct 2020 COVID-19 Tanta University Unknown No outcome recorded
Phase 14 trials
Phase 1 NCT07674446 Jun → Aug 2026 overdue Keri Pharma Hungary Kft Recruiting No outcome recorded
Phase 1 NCT06125002 Jan → Mar 2024 Londrina State University Unknown No outcome recorded
Phase 1 NCT05736224 May → Sep 2023 skin cancer Yale University Completed No outcome recorded
Phase 1 NCT05158192 Nov → Dec 2021 Laboratorios Andromaco S.A. Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT06546111 Oct 2024 → Oct 2025 overdue Helicobacter pylori infectious disease Sadat City University Recruiting No outcome recorded
Phase 36 trials
Phase 3 NCT05942547 Jul → Oct 2023 metabolic dysfunction-associated steatohepatitis Tanta University Unknown No outcome recorded
Phase 3 NCT05626166 Dec 2022 → Nov 2023 ulcerative colitis Tanta University Unknown No outcome recorded
Phase 3 NCT05243706 Mar 2022 → Sep 2023 poisoning Ain Shams University Unknown No outcome recorded
Phase 3 NCT01532882 Jan 2012 → Mar 2013 chronic venous insufficiency Laboratoire Innotech International Completed No outcome recorded
Phase 3 NCT01321619 Jul → Dec 2011 chronic venous insufficiency, hemorrhoid Vidfarma Indústria de Medicamentos Ltda. Unknown No outcome recorded
Phase 3 NCT01110512 Oct → Dec 2010 chronic venous insufficiency Azidus Brasil Unknown No outcome recorded
Phase 45 trials
Phase 4 NCT07598214 Feb 2025 → Nov 2026 expected cancer, familial, with in vitro Radioresistance Beni-Suef University Recruiting No outcome recorded
Phase 4 NCT06579482 Nov 2024 → May 2025 chronic venous insufficiency Fundação Educacional Serra dos Órgãos Completed No outcome recorded
Phase 4 NCT07588828 Oct 2024 → Feb 2026 female breast carcinoma Ittefaq Hospital trust Completed No outcome recorded
Phase 4 NCT03413618 Dec 2017 → Jul 2019 post-thrombotic syndrome, venous thromboembolism Pirogov Russian National Research Medical University Completed No outcome recorded
Phase 4 NCT03471910 Jun 2017 → Mar 2018 venous insufficiency Fundação Educacional Serra dos Órgãos Completed No outcome recorded
Phase not applicable2 trials
NCT06256575 May 2025 → Jul 2027 expected chronic ulcer of skin, systemic sclerosis Primus Pharmaceuticals Recruiting No outcome recorded
NCT07300735 Mar 2025 → Mar 2027 expected hematopoietic and lymphoid cell neoplasm, neutropenia Alexandria University Recruiting No outcome recorded
Also used as a comparator or background therapy in 12 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT02616731 Comparator Sep 2015 → Jan 2016 menstrual disorder Ain Shams University Unknown No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT02134249 Comparator Apr 2014 → Sep 2015 infertility disorder Benha University Completed No outcome recorded
Phase 36 trials
Phase 3 NCT06811220 Comparator Jan → Dec 2025 overdue breast cancer Alexandria University Not yet recruiting No outcome recorded
Phase 3 NCT06584799 Comparator Dec 2024 → Jan 2025 overdue pelvic congestion syndrome Pirogov Russian National Research Medical University Recruiting No outcome recorded
Phase 3 NCT05756179 Comparator Jul 2023 → Sep 2025 overdue rheumatoid arthritis Alexandria University Recruiting No outcome recorded
Phase 3 NCT05670457 Comparator Jun 2022 → Jun 2024 peptic ulcer disease Tanta University Unknown No outcome recorded
Phase 3 NCT07369635 Comparator Jul → Sep 2020 internal hemorrhoid Hanoi Medical University Completed No outcome recorded
Phase 42 trials
Phase 4 NCT02782455 Comparator Dec 2016 → Nov 2018 hemorrhoid Services Hospital, Lahore Completed No outcome recorded
Phase 4 NCT01654016 Comparator Aug 2012 → May 2019 chronic venous insufficiency University Hospital Dubrava Completed No outcome recorded
Phase not applicable2 trials
NCT06333691 Comparator Oct 2022 → Feb 2024 ovarian hyperstimulation syndrome Minia University Completed No outcome recorded
NCT04933591 Comparator Sep 2020 → Aug 2021 varicose disease Pirogov Russian National Research Medical University Completed No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 32 sources stand behind the page.

FieldValueCited text
Known as Diosmin “Patients will receive standard triple therapy (Omeprazole 20 mg cap PO BID + Clarithromycin 500 mg tab PO BID + Amoxicillin 1000 mg PO BID) and Diosmin/Hesperidin (Daflon)...” NCT06546111
25

“The sunscreen contains bioadhesive nanoparticles (BNP) encapsulating avobenzone and octocrylene plus the non-toxic natural products diosmin, ferulic acid, cytisine and...” NCT05736224

diosmin , 2 tablets (500mg) t.d.s for 2 weeks in addition to cabergoline 1 tablet 0.5 mg/day orally for 8 days starting at the day of hCG injection” NCT06333691

Diosmin 450mg and Hesperidin 50mg Tablets in Chronic Venous Insufficiency After 3 Months of Therapy” NCT06579482

Diosmin (450 mg) + hesperidin (50 mg)” NCT01110512

“Active substance: Diosmin 1000 mg.” NCT07674446

NCT02134249

NCT07588828

NCT05756179

NCT05670457

NCT06256575

NCT05942547

NCT07369635

NCT05626166

NCT06811220

NCT06584799

NCT06125002

NCT04452799

NCT05243706

NCT07598214

NCT01532882

NCT02616731

NCT01477281

NCT03471910

NCT04933591

NCT03413618

Known as Daflon “Control Group: Participants receiving Daflon (Diosmin).” NCT07369635
2

Daflon is administered” NCT02782455

NCT01321619

Known as Detralex ClinicalTrials.gov intervention name — accepted as the source's own label NCT01654016
Known as Diosmin-Hesperidin ClinicalTrials.gov intervention name — accepted as the source's own label NCT07300735
Known as Diosmin/Hesperidin (90/10) ClinicalTrials.gov intervention name — accepted as the source's own label NCT05158192
Known as DIOVENOR “The aim of this project led by Dr. Guex is to evaluate the efficacy and safety of diosmin 600 mg - DIOVENOR® on the painful symptoms of CVD of the lower limbs, in a...” NCT01532882
Known as DSM “Era evaluate the effects of supplementation with the flavonoid diosmin (DSM) on athletic performance and DOMS-related symptoms in the pre-season of a futsal team from the...” PMID 40818103 Aug 2025
Modality Small molecule “flavonoids combination (diosmin and hesperidin)” NCT05756179
Route Oral “Administered one tablet two times daily (oral)” NCT01321619