Drugs / XYF19 CAR-T cell
last change Aug 2024 re-read 3 minutes ago

XYF19 CAR-T cell

Cell therapy targets CD19, MAP4K1

Developed for
acute lymphoblastic leukemia · B-cell non-Hodgkin lymphoma
Investigated by
Xi'An Yufan Biotechnology Co.,Ltd · Xijing Hospital

Trials 1

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04037566 Aug 2019 → Aug 2021 B-cell non-Hodgkin lymphoma, acute lymphoblastic leukemia Xijing Hospital Unknown No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as XYF19 CAR-T cell ClinicalTrials.gov intervention name — accepted as the source's own label NCT04037566 ↗
Modality Cell therapy “CD19-specific CAR-T cells” NCT04037566 ↗
Route Intravenous “administered by IV injection” NCT04037566 ↗
Target CD19 “Autologous T cells engineered to specify CD19 transduced with a lentiviral vector and electroporated with CRISPR guide RNA to disrupt expression of endogenous HPK1” NCT04037566 ↗
Target HPK1 “Autologous T cells engineered to specify CD19 transduced with a lentiviral vector and electroporated with CRISPR guide RNA to disrupt expression of endogenous HPK1” NCT04037566 ↗