Drugs / LY3405105
last change Jan 2024 re-read 3 minutes ago

LY3405105

targets CDK7 via inhibition

Developed for
cancer
Investigated by
Eli Lilly and Company

Trials 1

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03770494 Jan 2019 → Feb 2021 cancer Eli Lilly and Company Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as LY3405105 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03770494 ↗
Action Inhibit “a covalent inhibitor of cyclin-dependent kinase 7 (CDK7)” PMID 37531083 ↗ Jan 2024
Route Oral “LY3405105 monotherapy was given once daily (QD; part A1) or thrice weekly (TIW; part A2) starting at 1 and 2 mg orally, respectively” PMID 37531083 ↗ Jan 2024
Target CDK7 “a covalent inhibitor of cyclin-dependent kinase 7 (CDK7)” PMID 37531083 ↗ Jan 2024