Drugs / C-CAR031
last change May 2026 re-read 2 minutes ago

C-CAR031

Cell therapy targets GPC3

Developed for
hepatocellular carcinoma · squamous cell lung carcinoma
Investigated by
Shanghai AbelZeta Ltd. · Zhejiang University

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT07444281 Dec 2024 → Apr 2027 expected squamous cell lung carcinoma Shanghai AbelZeta Ltd. Recruiting No outcome recorded
Phase 1 NCT05155189 Feb 2022 → May 2026 overdue hepatocellular carcinoma Zhejiang University Recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT06590246 Sep 2024 → Apr 2030 expected hepatocellular carcinoma Shanghai AbelZeta Ltd. Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as C-CAR031 “Patients in the dose escalation section will receive autologous C-CAR031 via intravenous (IV) infusion at DL1 and DL2.” NCT06590246
2

NCT07444281

NCT05155189

Modality Cell therapy “armored CART cell injection” NCT05155189
Route Intravenous “Autologous C-CAR031 administered by intravenous (IV) infusion” NCT05155189
Target GPC3 “Targeting GPC3 armored CART cell injection (C-CAR031)” NCT05155189