Drugs / PHIN-214
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PHIN-214

Developed for
cirrhosis of liver · fibrotic liver disease
Investigated by
PharmaIN

Trials 1

20222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05490888 Jan 2022 → May 2026 overdue cirrhosis of liver, fibrotic liver disease PharmaIN Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 4

DateIssuerRelease
2025-11-08 PharmaIN Results AASLD25 Poster Presentation: Phase 1, Single-Ascending Dose Results from the PHIN-001® Study of PHIN-214 in Compensated and Decompensated Patients with Cirrhosis. pharmain.com ↗
Phase 1, Single-Ascending Dose Results from the PHIN-001* Study of PHIN-214 in Compensated and Decompensated Patients with Cirrhosis.
2025-11-08 PharmaIN Results PharmaIN Corporation Showcases Phase 1 Single-Ascending Dose Results from PHIN-001 Study of PHIN-214 in Patients with Compensated and Decompensated Cirrhosis at the AASLD, The Liver meeting® 2025 pharmain.com ↗
PharmaIN Corporation, a clinical-stage biopharmaceutical company, today unveiled promising early results from the single-ascending dose phase of its Phase 1 trial of PHIN-214, a potential outpatient therapy for managing portal hypertension and its complications in patients with cirrhosis.
2024-11-18 PharmaIN Results PharmaIN Unveils Interim Phase 1b Clinical Data on the Activity and Safety of PHIN-214 in Decompensated Liver Cirrhosis at AASLD – The Liver Meeting® 2024 pharmain.com ↗
PharmaIN Corporation, a clinical-stage biopharmaceutical company dedicated to developing innovative subcutaneous peptide therapies, today introduced interim results from its ongoing Phase 1b clinical trial of PHIN-214 for the prevention and treatment of decompensated cirrhosis.
2024-05-28 PharmaIN Results Biomedicine & Pharmacotherapy: Subcutaneous therapy for portal hypertension: PHIN-214, a partial vasopressin receptor 1A agonist pharmain.com ↗
PHIN-214 enables once-daily subcutaneous administration without causing ischemia or tissue necrosis and has a 10-fold higher therapeutic index than terlipressin in healthy rats.

All press releases naming this drug 8 releases

DateIssuerRelease

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as PHIN-214 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05490888 ↗
Action Activate “It is a partial V1a agonist” NCT05490888 ↗
Route Subcutaneous “PHIN-214 is a terlipressin derivative administered subcutaneously.” NCT05490888 ↗