Drugs / SC-CAR4BRAIN
last change May 2023 re-read 3 minutes ago

SC-CAR4BRAIN

Cell therapy

Developed for
diffuse intrinsic pontine glioma
Investigated by
Seattle Children's Hospital

Trials 1

20242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05768880 May 2023 → Jan 2028 expected diffuse intrinsic pontine glioma Seattle Children's Hospital Active not recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as SC-CAR4BRAIN ClinicalTrials.gov intervention name — accepted as the source's own label NCT05768880 ↗
Modality Cell therapy “autologous CD4+ and CD8+ T cells lentivirally transduced to express to express combinations of B7-H3, EGFR806, HER2, and IL13-zetakine chimeric antigen receptors (CAR)” NCT05768880 ↗
Route Other “intraventricular CNS administered SC-CAR4BRAIN infusions” NCT05768880 ↗