Drugs / Anbal-cel
last change Nov 2025 re-read 3 minutes ago

Anbal-cel

Cell therapy targets CD19 via depletion

Developed for
diffuse large B-cell lymphoma · primary central nervous system lymphoma
Investigated by
Asan Medical Center · Hyungwoo Cho

Trials 1

20262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT07062627 Nov 2025 → Dec 2026 expected diffuse large B-cell lymphoma, primary central nervous system lymphoma Hyungwoo Cho Recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Anbal-cel ClinicalTrials.gov intervention name — accepted as the source's own label NCT07062627 ↗
Known as Anbalcabtagene autoleucel “Anbalcabtagene autoleucel (Anbal-cel) is an investigational autologous anti-CD19 CAR-T cell product” NCT07062627 ↗
Action Deplete “Upon CD19 engagement, Anbal-cel forms an immunological synapse and triggers effector functions, including proliferation, cytokine secretion (e.g., IFN-γ, IL-6, TNF-α, GM-CSF),...” NCT07062627 ↗
Modality Cell therapy “Anbalcabtagene autoleucel (Anbal-cel) is an investigational autologous anti-CD19 CAR-T cell product” NCT07062627 ↗
Route Intravenous “Anbal-cel will be administered as a single intravenous infusion on Day 1 within 30 minutes of thawing” NCT07062627 ↗
Target CD19 “incorporating a CD19-specific scFv” NCT07062627 ↗