Drugs / Muc1/CLL1/CD33/CD38/CD56/CD123-specific gene-engineered T cells
last change Jul 2025 re-read 3 minutes ago

Muc1/CLL1/CD33/CD38/CD56/CD123-specific gene-engineered T cells

Cell therapy targets CD33, CD38

Developed for
acute myeloid leukemia
Investigated by
Shenzhen Geno-Immune Medical Institute

Trials 1

202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT03222674 Jul 2025 → Jun 2028 expected acute myeloid leukemia Shenzhen Geno-Immune Medical Institute Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Muc1/CLL1/CD33/CD38/CD56/CD123-specific gene-engineered T cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT03222674 ↗
Modality Cell therapy “the patients' own T cells will be genetically modified with lentiviral vectors expressing chimeric antigen receptors” NCT03222674 ↗
Target CD33 “The multi-CAR T cells recognize specific molecules such as CD33, CD38, CD123, CD56, MucI, and CLL1, which are often found expressed on the surface of AML cells.” NCT03222674 ↗
Target CD38 “The multi-CAR T cells recognize specific molecules such as CD33, CD38, CD123, CD56, MucI, and CLL1, which are often found expressed on the surface of AML cells.” NCT03222674 ↗